circStau2b	circRNA	mus musculus	Stau2	mmu_circ_0000012	mm9_circ_000040		ATGTTTTCGGTGCAGCTGAGTCTTGGCGAGCAGACATGGGAATCCGAAGGGAGCAGTATAAAGAAGGCCCAACAAGCTGTTGCTAACAAAGCTTTGACTGAATCTACGCTTCCCAAACCAGTTCAGAAACCACCTAAAAGTAATGTCAATAATAACCCAGGTAGTATAACTCCAACTGTGGAACTGAATGGGCTCGCTATGAAAAGGGGAGAGCCTGCCATCTACAGGCCACTAGATCCAAAGCCATTCCCAAATTATAGAGCTAACTACAACTTCCGGGGCATGTACAATCAGAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	Another example is two conserved circRNAs from the RNA-binding protein Staufen 2 gene, which show differential expression among the analyzed tissues. While the longer circRNA isoform (containing exons 2每5, circRNA stau2a) is expressed in the majority of adult mouse tissues, the shorter, consisting of exons 4 and 5 (circRNA stau2b), is predominantly expressed in embryonic stem (ES) cells, embryonic tissues, and lung.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circStau2a	circRNA	mus musculus	Stau2	mmu_circ_0000013	mm9_circ_006026		TTTTGTGGAGCTGTGAGGGATACGGAAGTTTGATCAATATTGTCTTAACATGCTTCAGATAAATCAGCTTCTCTCCACGATAAAATGGCAAACCCCAAAGAGAAAACTCCAGTGTGTCTGGTAAATGAGTTAGCCCGTTTCCATAGCATCCAACCCCAGTATAAGCTTCTGAATGAAAGCGGGCCTGCTCATTCGAAGATGTTTTCGGTGCAGCTGAGTCTTGGCGAGCAGACATGGGAATCCGAAGGGAGCAGTATAAAGAAGGCCCAACAAGCTGTTGCTAACAAAGCTTTGACTGAATCTACGCTTCCCAAACCAGTTCAGAAACCACCTAAAAGTAATGTCAATAATAACCCAGGTAGTATAACTCCAACTGTGGAACTGAATGGGCTCGCTATGAAAAGGGGAGAGCCTGCCATCTACAGGCCACTAGATCCAAAGCCATTCCCAAATTATAGAGCTAACTACAACTTCCGGGGCATGTACAATCAGAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	Another example is two conserved circRNAs from the RNA-binding protein Staufen 2 gene, which show differential expression among the analyzed tissues. While the longer circRNA isoform (containing exons 2每5, circRNA stau2a) is expressed in the majority of adult mouse tissues, the shorter, consisting of exons 4 and 5 (circRNA stau2b), is predominantly expressed in embryonic stem (ES) cells, embryonic tissues, and lung. By northern blots, using probes detecting both linear and circular isoforms, we validated this circRNA to be specifically enriched in the brain, although its linear isoform mostly show much broader expression patterns across tissues. 	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circMfsd6	circRNA	mus musculus	Mfsd6	mmu_circ_0000037	mm9_circ_009434		ATCACCATTCAGAATTTTGAAGGTCACTGACCCTAATGGTGGTGGTAAGCCATGGCTGCTGATGATAAAGTTGCTATCCTAACTGATGATGAAGAGGAGCAGAAGAGAAAATATGTGCTTGCTGATCCCTTCAATGGCATCTGCAGGGAACCAGAACCACCTTCTAATGAAACCCCCTCCTCCACAGAGACCTCAGCCATTCCCGAGGAGGAAATAGACTGGATAGAGAAACATTGTGTGAAAGTCAACAATGACCTTCTCATCTCCAAGGTGTTTTATTTTTTCTTTTACTCTGCCTATGGCTCTCTTTACCCTCTCTTACCTGTATATTATAAACAGCTGGGAATGTCACCTAGCCAGAGTGGACTGTTGGTGGGCATTCGATACTTCATTGAATTCTGCAGTGCCCCCTTCTGGGGTGTAGTTGCAGATCGTTTCAGAAAGGGCAAAATTGTCCTCCTCTTTTCGCTTCTGTGTTGGGTTTTGTTCAACCTGGGCATTGGATTTGTCAAACCTGCTACCTTGAGATGTCTACCAAAGATCCCCCCAACAGCTCACCCCACCAATGTAAGTCACCCAGTAACTGTTCTGCCAATGAACTCCTCCACTGTCGCTTTCTTTAGCACACCACCAAAATTGCTCCAGAAAAGGGACGTGCAATTGTCTGAAACAGAGCCCAATATCTCAGACATAGATCTCGTGTCAACAGCATTGACCTTGACCAGTGAACCCACACGGAGGCCCCAGACAGAGGCAATTACCCACCCTGTTACAGGCTTGATTTTGAACACAAGCACAGTGACTCTGCCCCCCACAGGAAATGTCACCAGGGAGACAACCATTGCTGTGGTCACCACCACCAAATCTTTACCATCTGATCAAGTCACCCTTGTGTATGACCAACAGGAAGTTGAGGCGATATTCTTAATTATCTTAGTGGTTGTCATAATAGGAGAATTTTTCAGTGCCTCTTCTGTCACGATTGTAGATACAGTAACCCTCCAGTACCTGGGAAAACACCGAGACCGATATGGGCTACAGCGCATGTGGGGCTCCCTGGGCTGGGGCCTGGCCATGCTGTCTGTGGGTATTGGAATCGACTATACTCATATAGATGTGCTCATTGATGGGAAGGGGTGTAAGCCCCCTGAGTACCGGAACTACCAGATTGTCTTCATCGTCTTTGGAGTTCTCATGACCATGGCCCTGATCGTTGCCACTCAGTTCCGGTTCCGCTACAACCACTTCAACAATAGTGATGGTAAAGGGAAAGAGGTGGAGATCCCACAGGTGGAAAGGGACAACTCCACAGAGTCCTCTGAAGAGACTCCAACTGCCGCGACTCACTCACAGGCCTTCAACTTCTGGGACTTGATCAAGTTGCTATGCAGTGTGCAGTATGGCTCGGTTCTGTTTGTGGCCTGGTTCATGGGTTTTGGATACGGCTTCGTGTTCACCTTTCTCTACTGGCATCTGGAAGACCTAAATGGAACTACAACCCTCTTTGGGGTCTGTTCAGTCCTGAGTCATGTGTCCGAGTTGACCGCTTACTTCTTCAGCCACAAGCTTATTGAGTTGATTGGCCATATCAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	We selected several of the circRNAs, which showed a high CLR in at least one differentiation stage, and tested their expression changes with qRT-PCR and northern blots with independent biological replicates. As seen from the sequencing data, many of the analyzed circRNAs increase when linear transcript expression also increases (such as Mfsd6), but rarely by the same factor.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circCpsf6	circRNA	mus musculus	Cpsf6	mmu_circ_0000215	mm9_circ_008959		GAAGCAGAATATGGTGGACATGATCAGATAGATTTGTATGATGATGTCATCTCTCCATCTGCAAATAATGGCGATGCCCCAGAAGATCGCGACTACATGGATACTCTTCCACCAACTGTTGGTGATGATGTGGGTAAAGGAGCCGCACCAAACGTTGTGTACACTTACACTGGGAAGAGAATCGCATTGTATATTGGAAATCTAACATGGTGGACAACAGATGAGGACCTAACTGAGGCCGTTCATTCTTTGGGAGTAAATGATATTTTGGAGATAAAATTCTTTGAAAATCGGGCAAATGGACAATCAAAGGGATTTGCCCTTGTTGGTGTTGGATCTGAAGCATCTTCCAAAAAGTTAATGGATCTTTTGCCTAAAAGAGAACTTCATGGTCAGAGTCCTGTTGTAACTCCATGCAATAAGCAGTTCCTGAGTCAATTTGAAATGCAATCCAGGAAAACTACACAGTCAGGACAGATGTCTGGGGAAGGGAAAGCCGGTCCTCCAGGAGGCGGTTCACGCGCAGCGTTTCCTCAAGGTGGTAGAGGACGGGGCCGGTTTCCAGGGGCTGTTCCTGGTGGGGACAGATTTCCTGGGCCAGCAGGACCAGGAGGGCCACCTCCACCTTTTCCAGCTGGACAAACTCCACCACGTCCACCTTTAGGCCCACCTGGCCCACCTGGTCCACCAGGTCCTCCACCTCCTGGTCAGGTTCTGCCACCTCCTCTAGCAGGACCTCCTAACCGAGGAGACCGCCCTCCACCACCAGTTCTTTTTCCTGGACAACCTTTTGGGCAGCCTCCGCTGGGTCCACTTCCTCCTGGGCCTCCACCTCCAGTTCCAGGCTACGGCCCCCCTCCAGGTCCACCGCCTCCACAGCAGGGACCACCTCCACCTCCAGGCCCCTTTCCACCTCGCCCACCAGGTCCACTAGGGCCTCCCCTCACACTTGCTCCTCCTCCACATCTTCCGGGACCACCTCCAGGTGCCCCGCCACCAGCTCCACATGTGAATCCTGCTTTTTTTCCTCCACCAACTAATAGTGGCATGCCAACATCAGATAGTCGAGGTCCACCACCAACAGACCCATATGGCCGACCTCCCCCATATGATAGGGGTGACTACGGTCCCCCTGGGAGGGAAATGGATACTGCAAGAACACCTCTGAGTGAAGCTGAGTTTGAAGAAATCATGAATAGAAATCGGGCAATCTCAAGCAGTGCTATTTCAAGAGCTGTGTCTGACGCTAGTGCTGGTGATTATGGGAGTGCTATTGAAACATTGGTAACAGCAATTTCTTTAATTAAACAATCCAAAGTCTCTGCAGATGATCGTTGCAAAGTTCTTATTAGCTCTCTGCAGGATTGCCTTCATGGAATCGAGTCCAAGTCCTATGGGTCTGGATCCAGACGTGAACGATCAAGAGAACGGGACCATAGTAGATCACGGGAAAAGAGTCGTCGCCATAAATCTCGGAGTAGAGATCGCCACGATGACTATTACAGAGAGAGAAGCAGAGAACGAGAGAGACACCGGGATCGGGACCGCGACCGTGACCGAGAGCGTGACCGAGAGCGAGAATACCGTCATCGTTAGAAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	By northern blots, using probes detecting both linear and circular isoforms, we validated this circRNA to be specifically enriched in the brain, although its linear isoform mostly show much broader expression patterns across tissues.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
mmu_circHECTD1	circRNA	mus musculus	Hectd1	mmu_circ_0000375	mm9_circ_002888		GAAGAAGAAGAGTATGAAACCAAAGGAGGCCGCCGCAGAGCCTGGGATGACGACTATGTGCTAAAGCGCCAGTTTTCTGCACTGGTCCCTGCTTTTGATCCTAGACCTGGTCGTACCAATGTCCAGCAGACAACTGACCTAGAAATTCCTCCCCCAGGAACACCTCACTCAGAGCTCTTGGAGGAAGTTGAATGTACTCCGTCACCTCGCTTGGCTCTCACACTGAAAGTGACGGGGCTTGGAACAACGCGGGAAGTTGAACTGCCACTTACCAATTTCAGATCCACCATCTTTTACTATGTACAAAAACTGCTTCAACTGTCTTGTAATGGCAATGTGAAGTCAGATAAACTTAGGCGTATTTGGGAGCCCACTTACAC	silicosis	29290828	circRNA Mediates Silica-Induced Macrophage Activation Via HECTD1/ZC3H12A-Dependent Ubiquitination.	Zhou Z, Jiang R, Yang X, Guo H, Fang S, Zhang Y, Cheng Y, Wang J, Yao H, Chao J.	Theranostics.  2018	mmu_circHECTD1 expression varied in the lungs of mice in the NS group and SiO2 group. mmu_circHECTD1 expression decreased after 24 h of SiO2 exposure in RAW264.7 cells. These results were confirmed in a fluorescence in situ hybridization (FISH) assay, in which mmu_circHECTD1 was mainly detected in the cytoplasm of RAW264.7 cells. mmu_circHECTD1 was significantly decreased after 7 and 28 days compared with the levels in NS-treated mice.	microarray, qRT-PCR, FISH	the lungs of mice, RAW264.7 cells	SiO2 concomitantly decreased circHECTD1 levels and increased HECTD1 protein expression. circHECTD1 and HECTD1 were involved in SiO2-induced macrophage activation via ubiquitination; and SiO2-activated macrophages promoted fibroblast proliferation and migration via the circHECTD1/HECTD1 pathway. Tissue samples from silicosis patients confirmed the upregulation of HECTD1.	loss of function, gain of function	RAW264.7 cells, 	mouse lungs	Human bronchoalveolar lavage fluid of patients with silicosis	ZC3H12A	circRNA-protein	RAW264.7 cells	RIP	ZC3H12A interacted with circHECTD1 but not HECTD1 mRNA.		
circHECTD1	circRNA	mus musculus	Hectd1	mmu_circ_0000375	mm9_circ_002888		GAAGAAGAAGAGTATGAAACCAAAGGAGGCCGCCGCAGAGCCTGGGATGACGACTATGTGCTAAAGCGCCAGTTTTCTGCACTGGTCCCTGCTTTTGATCCTAGACCTGGTCGTACCAATGTCCAGCAGACAACTGACCTAGAAATTCCTCCCCCAGGAACACCTCACTCAGAGCTCTTGGAGGAAGTTGAATGTACTCCGTCACCTCGCTTGGCTCTCACACTGAAAGTGACGGGGCTTGGAACAACGCGGGAAGTTGAACTGCCACTTACCAATTTCAGATCCACCATCTTTTACTATGTACAAAAACTGCTTCAACTGTCTTGTAATGGCAATGTGAAGTCAGATAAACTTAGGCGTATTTGGGAGCCCACTTACAC	pulmonary silicosis	29540674	circHECTD1 promotes the silica-induced pulmonary endothelial-mesenchymal transition via HECTD1.	Fang S, Guo H, Cheng Y, Zhou Z, Zhang W, Han B, Luo W, Wang J, Xie W, Chao J.	Cell Death Dis.  2018	SiO2 induced a rapid increase in circHECTD1 expression in MML1 cells, which was confirmed using FISH. Moreover, SiO2 also induced circHECTD1 expression in human endothelial cell line-HUVECs.	qRT-PCR, FISH	MML1 cells, human endothelial cell line-HUVECs	SiO2 concomitantly increased circHECTD1 expression, which, in turn, inhibited HECTD1 protein expression. SiO2-induced increases in cell proliferation, migration, and changes in marker levels were restored by either a small interfering RNA (siRNA) targeting circHECTD1 or overexpression of HECTD1 via the CRISPR/Cas9 system, confirming the involvement of the circHECTD1/HECTD1 pathway in the EndMT.	loss of function	MML1	Tie2-GFP mice exposed to SiO2 and silicosis patients	silicosis patients							
circMyst4	circRNA	mus musculus	Myst4	mmu_circ_0000505	mm9_circ_008231		GTCTTGGTTTCCTAAAGATGTCTTTCACTTGAAGAGTGCAGTCCTTCCCATTGGTGAACTAAGACAACTCTCCACGTTGCCTGGCAGTCAGTCCTCTCTTTAAGGATGGTTGTCCCTATGCTGTTGCTTCACATGGGCTGGGATCCTCTGCCCTTGTGTTGAATTGTGACTTTGGAATGTGCAGGTTGTGTTAAGTACAAGGCGAATCTCTATGGGTAACGTCTGTGTTGGAGAAGCCATTTGTCAACCATGGTAAAACTTGCAAACCCACTTTACACAGAGTGGATTCTTGAAGCAGTGCAGAAAATCAAGAAGCAGAAGCAGCGGCCCTCAGAAGAGAGGATCTGCCATGCGGTCAGCACGTCCCATGGGTTGGACAAGAAAACAGTCTCGGAACAGCTGGAACTTAGTGTTCAGGATGGCTCCGTTCTCAAAGTCACCAACAAAGGCCTTGCTTCATATAAGGACCCAGACAATCCTGGGCGTTTTTCATCGGTTAAACCGGGCACTTTCCCCAAGCCAACCAAGGGGTCCAAAGGACCGCCGTGTAATGATCTACGCAATGTGGATTGGAATAAACTTTTAAAGAGAGCAATCGAAGGCCTTGAGGAGCCAAACGGCTCCTCCTTGAAGAACATTGAGAAGTATCTGAGAAGCCAGAGTGATCTTACAGGCACCACCAACCATCCAGCCTTTCAGCAGAGGTTGCGGCTAGGGGCCAAGCGTGCTGTGAACAATGGGAGGTTACTGAAGGAAGGACCACAGTACAGGGTCAATAGTGGGAGCTCAGATGGCAAAGGGGCGCCCCAGTACCCCAGTGCTTTTCCGTCCTCACTCCCGCCCGTCAGCCTTCTACCCCATGAGAAAGACCAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	Numerous circRNAs were found as the predominant isoform in brain, such as circMyst4.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circRims2	circRNA	mus musculus	Rims2	mmu_circ_0000595	mm9_circ_011266		GTGCTATGGATATAGAGGAGAGAAATCGCCAAATGAAACTTAACAAATACAAACAGGTAGCCGGATCAGACCCCAGACTGGAGCAAGATTACCATTCGAAGTATCGCTCAGGATGGGATCCACATAGAGGGGCAGATACTGTTTCCACTAAATCCTCGGACAGTGATGTAAGTGATGTATCTGCGGTTTCAAGGACTAGTAGTGCTTCTCGTTTCAGCAGCACAAGCTACATGTCCGTCCAATCAGAGCGGCCGAGAGGAAACAGGAAAATCAGTGTCTTTACATCCAAAATGCAAAACAGACAGATGGGCGTGTCGGGGAAGAACTTGACCAAAAGCACCAGCATCAGTGGAGACATGTGCTCACTGGAGAAGAATGACGGCAGCCAGTCCGACACTGCAGTGGGCGCCCTGGGTACCAGTGGCAAGAAGCGGCGATCTAGCATTGGGGCCAAAATGGTAGCTATTGTTGGTCTCTCACGGAAAAGTCGCAGTGCCTCTCAACTCAGCCAAACCG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	A striking example is the mouse circRNA generated from Rims2. In the adult brain, it is expressed  20-fold higher than the linear mRNA, but is lowly expressed in other mouse tissues. By northern blots, using probes detecting both linear and circular isoforms, we validated this circRNA to be specifically enriched in the brain, although its linear isoform mostly show much broader expression patterns across tissues. We found several circRNAs enriched in specific brain regions〞independent of their linear isoforms. Some circRNAs were highly enriched in the cerebellum: circRims2, circElf2, and circDym, while circPlxnd1 was enriched in the cortex. circRims2 was detected exclusively in the granular layer of the cerebellum. 	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circTulp4	circRNA	mus musculus	Tulp4	mmu_circ_0000723	mm9_circ_008009		AGTTGTAAGAGTCCATCCAGGACCTTCCAGTCATGAATAATCTGATGGCTCCTGAATTAACCGGGAAAACAAACATATCAAGTGCCATTTGAAGACTCTGTCTATCTATGTAAAACCTTTTCTGCACATAGAAGCTTTTCCATAAGAAGACATTCTGAATTTTGCAACTGATGAAGATTAAGCATCAGCTGGAGCACCTTTCCACTGTTGGGGTTGGGAGTCTGTGGAGAACAGTCTGTCACTAATGTCAGATTTTCCTTACAGTGTTCATAAACAAAAGCCAGTTTGCAAAAGAAAAAATTGCACAGATTAACCCTAAAGAATAGCTCCAGTGTAAAGCAGGGGCAGACCTTAAAACTCTGAACCGGAGCTCAGTGACTTTTCCTGTGGTTGTAGCAGGAGTGAGGGGACTGATCTGAAAGGAACAGATTCCTTTGTGTCTTCAGCTATCGGAAGTTTTTTATTTATTGTTTATCTTTTTTCTTTTCTGCATATATATGCCATTTTAAAATACTAATTGGAACTGTCAGTTACAAAATAAATATCAAGAAAAGCCTTTTTTGGTCCAAAGGTGTGAACAGGCTTGCAGGTGAACAGGAAGACATCTTTGGTAAAGCTTGGACCGGTCTTGGGAGATGGTGCATCTTGGAGGGCTCTGCTACACGCCTAGGTGGCTGGTTTAAAGGCTTGCATCGCAGACGGAGACTAATTAATAGACACAGTTCTAAGATTGCTTTTTCATTAACATAGAAACTAGAGAAAGGAGAAACAGAAGCCTGCAGCCTAGTCTGTGTAAGCAAGAAGTAGGACCAAACTGAGGAAACTACTTGGTCCATTTAGATAGCAGTTTATTCATACTCAGTGACCCGCAGGCCTCCACCTCTGCTTGAGGGAAGGGCTTTGCTCCAGTCTCTGTGGCACTGAGGGTGGTTCCAGCCCATGGAGGAGTCATTCTAGGAAGCCCTGTGTTCCTAGGGACACAGGGCCAGGCTTTGAGACAGGAAGCTTCTGGCTGTGAGCAGTGGGGGAAAGAGTGATTTTCTTGTTAAAGCTTTGACCATTGTCTGCATGAGCTCTGGTGTGACTTTGCACGTTAGTGTGCCTTTCCCCTTATGCAACCTTTTCCAGCTTACAGCAGAAACTTGCCGAGTTCAGAAAACGTGCCAGAGGGTGGCTTCAGAGGGAAGATGATCTTGTGTGATCAGTCTCTGCACTTGAACTATTGAATAGAGAAATCCAGCTAGAGGAATTCTTACCGCCTTAAGTTACTTGAAATCTATGTGTTTGTAACCCTTTGTCTCTGGAATTACATTACAAAAAAAACTGGAATCTCAGGCTGAGAATAACGAGGCTGAGTAAAAGCGAAGAGAACTGCCTCTTCATCATCACTTACTAACAGCTCTTTCTCCAAAGGATTGGTGTGGTTTCCCGCTAAGAACTTGAAAATGAGAACGGACCCTGTGTATTTTTAGGCATTACCTTTCTTCGCCGACTGACGTCTTTTATAGAGGAGTTTTTTCACTATGCATTTGGTGGAGCTTTATAAGCTATTGACCTAATTGGACTCTAGATCAGTTGTAACTAAAGGAGAAAAAAACAAACCAACGGAACCCAACCACAAAAATAAGCCAATAAAAGAACTTGGTTTGAAATTCCTCAGTACTTTTAAAGTGAAATACTTCATTGAAAAAAGTATGTATGCAGCAGTGGAACATGGGCCTGTGCTTTGCAGCGATTCCAACATCCTCTGCCTGTCCTGGAAGGGGCGTGTTCCCAAGAGTGAGAAGGAGAAACCTGTGTGCAGAAGGCGCTACTATGAAGAGGGATGGTTGGCCACAGGCAATGGGCGAGGTGTGGTGGGAGTGACTTTCACCTCGAGTCACTGTCGCAGAGATAGGAGTACACCACAGAGAATAAACTTCAACCTGCGAGGCCACAACAGTGAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	Numerous circRNAs were found as the predominant isoform in brain, such as circTulp4.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circVim	circRNA	mus musculus	Vim	mmu_circ_0000978	mm9_circ_016723		ACATGGCTTCGAAGGTGGGCTGGCTTGCTGCGGCTGGAAAAACTGCAACAAGGGAATGAGGGCGCGGTGGCTGTGAATCGTAGGAGCGCTGGGGTCTCTGGG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	circVim was validated experimentally.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
mmu_circ_0001028	circRNA	mus musculus	Stk39	mmu_circ_0001028	mm9_circ_017329		GCAGCGGAGCAACTGCGGTGGTTCAGGCAGCCCTATGCAAACCCAGGCAAGAACGCGTAGCCATAAAGCGGATCAACTTGGAAAAATGCCAGACGAGTATGGATGAACTCCTGAAAGAAATTCAAGCCATGAGCCAATGCAGCCATCCCAACGTAGTGACTTATTACACCTCCTTTGTGGTCAAAGATGAGCTGTGGCTGGTCATGAAATTACTAAGTGGAGGTTCCATGTTGGATATCATCAAATACATCGTTAATCGAGGAGAACATAAAAATGGTGTCCTAGAAGAGGCGATAATTGCAACAATTCTTAAGGAGGTTTTGGAAGGTTTAGACTATCTGCACAGAAACGGTCAGATCCATAGGGATTTGAAAGCTGGAAATATTCTTCTGGGTGAGGATGGCTCAGTACAAATAGCAG	pulmonary toxicity induced by radon	29165116	Circular RNA profiles in mouse lung tissue induced by radon.	Pei W, Tao L, Zhang LW, Zhang S, Cao J, Jiao Y, Tong J, Nie J.	Environ Health Prev Med.  2017	The expressions of the circRNA was examined in mice of 60 WLM group.	microarray, qRT-PCR	BALB/c mice lung tissue												
circPhf21a	circRNA	mus musculus	Phf21a	mmu_circ_0001047	mm9_circ_006097		GGGACTGGAGAGCTGAAGGAGCGCCAGCTTCTCCAGAATTGGACTTCTCAGAACCTTTAATATGCTAATGTGCATTGTGAATCTCCAAGATGGGGATATGATATGCAGCATTCTTGAATACTTCTAATGACAGGGAGCCCACTACCTCATAAGCTGCAGCAACAAGAGGAGCTTGTAATTTTAAACGGAGGCTGAAGACACTGTAGAATTAGCAGACATAAGAGAGCGTGGAGAAGGCAGAGGATGGAGTTGCAGACTCTACAGGAGGCTCTTAAAGTGGAAATTCAGGTTCACCAGAAACTGGTTGCCCAAATGAAGCAGGATCCACAGAATGCTGACTTAAAGAAACAGCTTCATGAACTCCAAGCCAAAATCACAGCTTTGAGTGAGAAACAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	By northern blots, using probes detecting both linear and circular isoforms, we validated this circRNA to be specifically enriched in the brain, although its linear isoform mostly show much broader expression patterns across tissues. circElf2 and circPhf21a showed predominant expression in the granular layer of cerebellum and olfactory bulb, consistent with qRT-PCR and northern blot analysis	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circDLGAP4	circRNA	mus musculus	Dlgap4	mmu_circ_0001098	mm9_circ_015028		GTTCATCATGCCTAGTGGCATATAAGAAGACCCCACCACCGGTCCCTCCACGAACCACATCGAAACCGTTCATCTCAGTCACCGTCCAGAGCAGTACTGAGTCTGCTCAGGATACCTACCTGGACAGTCAAGACCACAAGAGCGAAGTGACGAGCCAGTCGGGCTTGAGCAACTCATCAGACAGCCTGGACAGCAGTACCCGGCCACCCAGTGTGACACGGGGTGGAATTACCCCAGGCCCTGAAGCTCCGGAGCCACCCCCTAAGCATGCAGCTCTGAAGAGTGAACAAGGGACACTGACGAGCTCTGAGTCCCATTCCGAGGCCATCCCCAAAAGGAAACTGTCATCGATAGGAATACAAGTTGACTGCATTCAGCCAGTGCCAAAAGAGGAGCCCAGTCCCGCTACCAAATTCCAGTCCATCGGGATTCAGGTAGAGGACGACTGGCGAAGCAGTGCCCCCTCTCACAGCATGTCCTCCCGTCGGGACACTGACTCTGATACCCAGGATGCCAACGACTCCAGTTGTAAGTCATCTGAGAGGAGTCTCCCAGACTGTACCTCACACCCCAATTCCATCAGCATTGATGCTGGCCCCCGACAGGCCCCCAAGATTGCCCAGATCAAGCGCAACCTCTCCTATGGAGACAACAGCGACCCTGCCCTGGAGGCGTCTTCGCTGCCCCCACCCGACCCTTGGCTGGAGACTTCCTCCAGCTCCCCAGCAGAGCCCGCTCAGCCAGGGGCCTGCCGCAGGGATGGCTACTGGTTCCTGAAGCTCCTTCAGGCAGAAACGGAGAGACTGGAAGGCTGGTGCTGCCAGATGGACAAGGAGACCAAAGAGAACAACCTCTCTGAAGAAG	acute ischemic stroke	29114076	Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.	Bai Y, Zhang Y, Han B, Yang L, Chen X, Huang R, Wu F, Chao J, Liu P, Hu G, Zhang JH, Yao H.	J Neurosci.  2018	circDLGAP4 levels in these AIS subjects were significantly decreased compared with those in age- and gender-matched cognitively healthy controls. There were no gender-based differences in circDLGAP4 levels. Consistent with these clinical findings, circDLGAP4 expression levels were observed to be decreased in the ipsilateral hemispheres of mice with tMCAO compared with those in the sham group at 24 h after reperfusion. This was further confirmed by Northern blotting.	qRT-PCR, northern blots 	healthy controls and AIS patients, brain tissues of tMCAO mice	circRNA DLGAP4 (circDLGAP4) functions as an endogenous microRNA-143 (miR-143) sponge to inhibit miR-143 activity, resulting in the inhibition of homologous to the E6-APC-terminal domain E3 ubiquitin protein ligase 1 expression. Upregulation of circDLGAP4 expression significantly attenuated neurological deficits and decreased infarct areas and blood每brain barrier damage in the transient middle cerebral artery occlusion mouse stroke model. Endothelial-mesenchymal transition contributes to blood每brain barrier disruption and circDLGAP4 overexpression significantly inhibited endothelial-mesenchymal transition by regulating tight junction protein and mesenchymal cell marker expression.	gain of function	HEK293T, bEnd.3 	tMCAO mice	healthy controls and AIS patients	miR-143	circRNA-miRNA	HEK293T, bEnd.3 	RNA pull-down, FISH	More circDLGAP4 enrichment was detected in the miR-143-captured fraction than in the fractions in which mutations disrupted base-pairing between circDLGAP4 and miR-143 in both HEK293T and bEnd.3 cells. This finding was further confirmed via FISH, demonstrated by colocalization between circDLGAP4 and miR-143 in cytoplasm.	HECTD1	
circElf2	circRNA	mus musculus	Elf2	mmu_circ_0001125	mm9_circ_005039		TAGTTCCAGAGAACCTGCTGGTTTAGAGTTTAGCTCTTGGGAGTTGTGAAAACAGTGAAGGATGCTTAGACTACTTAACATTCAAACTACCCTCTGGTTAATCACCTTTAGAAGACTGGACTTCCGGATGTCTACTCCATCTCTATTGAACTAAACCATGAAAATGAAGGCTACAGTCCTGGCAATCGTCTGTGAGCCTTAGTTCCGTTGCTTCACAGCATTTGAGACTTCCTCAGGGAACGCACGATGGCATCGGCGGTGGTTGACAGCGGAGGCTCTGCTCTGGAGCTTCCTAGCGATGGAGGAGAAAATCAAGAGGGAGGTGACACGGGCCCTGACTGCCCGGCAGTGATTGTGGAGCCAGTTCCCAGTGCGAGGTTAGAGCAGGGCTATGCTGCCCAGGTGCTGGTCTATGACGACGAGACTTATATGATGCAGGATGTGGCGGAAGAACAGGAAGTTGAGACGGAGAATTCAGAAACAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	By northern blots, using probes detecting both linear and circular isoforms, we validated this circRNA to be specifically enriched in the brain, although its linear isoform mostly show much broader expression patterns across tissues. We found several circRNAs enriched in specific brain regions〞independent of their linear isoforms. Some circRNAs were highly enriched in the cerebellum: circRims2, circElf2, and circDym, while circPlxnd1 was enriched in the cortex. CircElf2 and circPhf21a showed predominant expression in the granular layer of cerebellum and olfactory bulb, consistent with qRT-PCR and northern blot analysis.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
mmu_circ_0001152	circRNA	mus musculus	Fam46c	mmu_circ_0001152	mm9_circ_006065		CTGTCTAGGGGCCGCAGTCTCCGCTCCGCTCCTGCTGGGGGCTGCCCACGCCAACCACCTGCCTCAGTCACCTCCTCTTCCAACGCCCAG	pulmonary toxicity induced by radon	29165116	Circular RNA profiles in mouse lung tissue induced by radon.	Pei W, Tao L, Zhang LW, Zhang S, Cao J, Jiao Y, Tong J, Nie J.	Environ Health Prev Med.  2017	The expressions of the circRNA was examined in mice of 60 WLM group.	microarray, qRT-PCR	BALB/c mice lung tissue												
mmu_circ_0001154	circRNA	mus musculus	Cept1	mmu_circ_0001154	mm9_circ_007135		CCCCCAGGTAAATAGCCACAGAAGGCTACCAAACAAGATAAATAATTGTCTCCAAGTAGAAGAAAACCAAGCTCCATGAGTGGGCATCGGTCAACAAGGAAACGATGTGGAGATTCTCACCCAGAGTCCCCTGTGGGCTTTGGGCATATGAGTACTACAGGGTGTGTATTAAATAAATTGTTTCAGTTACCGACACCACCACTGTCAAGACACCAGTTAAAACGGCTAGAAGAACACAGGTATCAGAGTGCTGGACGGTCCCTTCTCGAGCCCTTAATGCAAGGATACTGGGAATGGCTAGTTGGAAGAGTACCCTCATGGATTGCCCCAAATCTCATCACCATCATTGGACTATCAATAAATATCTGTACAACTATTTTGTTAGTCTTCTACTGCCCTACAGCTACAGAGCAGGCACCTCTGTGGGCTTATATTGCCTGTGCTTGTGGCCTTTTCATTTACCAGTCTCTGGATGCCATAGATGGGAAACAGGCCAGAAGAACTAACAGTAGCTCTCCTCTGGGAGAACTTTTTGATCATGGCTGTGACTCACTATCGACAGTTTTTGTGGTTCTTGGAACTTGTATTGCAGTACAACTTGGGACAAATCCTGACTGGATGTTTTTTTGTTGTTTTGCTGGGACATTCATGTTCTATTGTGCACACTGGCAAACATATGTTTCTGGAACATTGCGATTTGGAAT	pulmonary toxicity induced by radon	29165116	Circular RNA profiles in mouse lung tissue induced by radon.	Pei W, Tao L, Zhang LW, Zhang S, Cao J, Jiao Y, Tong J, Nie J.	Environ Health Prev Med.  2017	The expressions of the circRNA was examined in mice of 60 WLM group.	microarray, qRT-PCR	BALB/c mice lung tissue												
mmu_circ_0001311	circRNA	mus musculus	Ankib1	mmu_circ_0001311	mm9_circ_000903		AATGTGAAACATGTTGTAGAAGTACTCAAGAAGTGGCTGAAGGAAGAAAGAACGTGCCACTGCCTATCAGAAAATAACAAAACATGGGAAATACAACCACCAAATTCCGCAAAGCACTCATCAATGGTGATGAAAATTTGGCCTGCCAAATATATGAAAATAATCCTCAGCTAAAAGAATCCCTTGATCCCAATATTTCTTATGGAGAACCCTATCAGCACAACACACCGTTACACTATGCTGCTAGACATGGAATGAATAGAATATTAGGGACTTTTCTTTTTGGTAGAGATGGAAACCCAAATAAACGGAATGTGCACAATGAAACATCTATGCATTTGTTGTGTATGGGACCTCAAATCATGATATCTGAAGGAACCCTTCATCCTCGCTTAGCACGGCCTGTGGAAGATGATTTCAGAAGGGCAGATTGTCTGCAGATGATCTTACAGTGGAAAGGAGCAAAACTTGACCAAGGCGAATATGAGAGAGCGGCTATTGATGCCGTTGATAACAAAAAGAACACACCCCTTCACTATGCTGCAGCCTCGGGGATGAAAGCCTGTGTAGAGCTCTTAGTAAAACATGGAGGAGACTTGTTTGCTGAAAATGAAAATAGAGATACTCCTTGTGATTGTGCCGAAAAGCAGCAGCACAAAGACCTGGCCCTCAGTCTGGAGTCTCAGATGGTGTTCTCTCGGGACCCGGAGGCCGAAGAAATAGAAGCGGAGTATGCTGCCTTAGACAAGCGAGAGCCATATGAAGGACTAAGGCCCCAGGATCTTCGTAGGTTAAAAGATATGCTTATTGTGGAGACTGCAGACATGCTCCAGGCCCCTCTGTTTACTGCTGAAGCACTGCTTCGAGCTCACG	pulmonary toxicity induced by radon	29165116	Circular RNA profiles in mouse lung tissue induced by radon.	Pei W, Tao L, Zhang LW, Zhang S, Cao J, Jiao Y, Tong J, Nie J.	Environ Health Prev Med.  2017	The expressions of the circRNA was examined in mice of 60 WLM group.	microarray, qRT-PCR	BALB/c mice lung tissue												
mcircRasGEF1B	circRNA	mus musculus	Rasgef1b	mmu_circ_0001367	mm9_circ_015601		GAAAGTATGCCTCAGACGCCCCCCTTCTCAGCAATGTTTGACAGCAGTGGCTACAACCGAAACCTCTACCAGTCCGCAGAGGACAGCTGTGGAGGCTTGTACTACCATGACAACAACCTCCTTTCTGGGTCTCTGGAAGCCCTTATCCAACACTTGGTACCCAATGTGGATTACTATCCTGATAGGACATACATCTTCACCTTCCTGCTTAGTTCTCGGTTATTCATGCATCCGTACGAGCTCATGGCTAAGGTTTGCCACCTGTGTGTTGAGCACCAGCGACTGAGTGAAGGGGACGGCGATAAGAACCAGATGAGAAAAATTGCACCTAAAATCCTTCAGCTCTTGACAGAGTGGACAGAAACATTTCCGTATGACTTCCGGGACGAGAGAATGATGAGGAACCTCAAGGACCTGGCGCACAGGATGGCCAGTGGCGAGGAG	microbial infections	28947785	Transcriptomic analysis of the role of RasGEF1B circular RNA in the TLR4/LPS pathway.	Ng WL, Marinov GK, Chin YM, Lim YY, Ea CK.	Sci Rep.  2017				Knockdown of mcircRasGEF1B results in altered expression of a wide array of genes. Pathway analysis revealed an overall enrichment of genes involved in cell cycle progression, mitotic division, active metabolism, and of particular interest, NF-百B, LPS signaling pathways, and macrophage activation. These findings expand the set of functionally characterized circRNAs and support the regulatory role of mcircRasGEF1B in immune response during macrophage activation and protection against microbial infections.	loss of function	RAW264.7 cells									
circSv2b	circRNA	mus musculus	Sv2b	mmu_circ_0001583	mm9_circ_005710		GCTGGGGCTTCAGCATGGGGACTAATTACCACTTCCACAGCTGGAGAGTGTTTGTCATCGTCTGTGCTCTGCCCGCCACTGTGTCCATGGTGGCTCTGAAGTTCATGCCAGAAAGCCCCAGGTTCCTGCTGGAGATGGGCAAACATGATGAAGCCTGGATGATTCTCAAACAAGTCCATGATACAAACATGAGAGCTAAGGGGACCCCGGAAAAGGTGTTCACGGTTTCCCACATCAAAACTCCCAAGCAAATGGATGAATTCATTGAGATACAGAGCTCAACCGGAACTTGGTACCAGCGCTGGCTGGTCAGGTTCATGACCATTTTCAAACAGGTCTGGGATAACGCCTTGTACTGTGTGATGGGGCCCTACAGAATGAACACCCTGATTCTGGCTGTGGTCTGGTTCACCATGGCCTTAAGTTACTACGGCCTGACGGTGTGGTTCCCCGACATGATCCGCTATTTCCAGGATGAAGAATATAAGTCTAAAATGAAGGTGTTTTTTGGTGAGCACGTGCATGGCGCCACGATCAACTTTACCATGGAAAACCAGATCCACCAACATGGGAAGCTTGTGAACGATAA		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	By northern blots, using probes detecting both linear and circular isoforms, we validated this circRNA to be specifically enriched in the brain, although its linear isoform mostly show much broader expression patterns across tissues.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circAmotl1	circRNA	mus musculus	Amotl1	mmu_circ_0001745	mm9_circ_000340		CCGGCCCTGCCAGCTGCCTTTTCCATCTACGGTGCAGCAGCATAGCCCCATGTCCTCTCAGACCTCCTCCATCGGTGGTACTCTGCACTCCGTCTCCCTGCCTCTTCCACTTCCCATAAGCCTGGCGGCTTCACAGCCCCTACCAGCCTCCCCCAACCAGCAGCTTGGACCGGATGCCTTTGCGATTGTGGAGCGAGCCCAGCAAATGGTAGAGATCCTGACAGAGGAGAACCGTGTGCTTCACCAGGAGCTTCAGGGCTGCTATGACAACGCTGACAAGCTCCACAAGTTTGAAAAAGAGCTGCAGAGTATTTCGGAGGCCTACGAGAGCCTGGTCAAGTCCACCACCAAGCGTGAGTCTCTGGACAAGGCAATGAGAACCAAGCTCGAAGGCGAGATAAGGAGACTTCATGACTTCAACAGAGATCTCCGAGATCGACTGGAGACAGCCAACAGGCAGCTGTCCAGCAGGGAATACGATGGGCATGAAGACAAAGCTGCAGAGAGCCATTACGTGTCCCAGA	wound healing	28676341	The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function.	Yang ZG, Awan FM, Du WW, Zeng Y, Lyu J, Wu, Gupta S, Yang W, Yang BB.	Mol Ther.  2017				Expression of the circular RNA circ-Amotl1 accelerated healing process in a mouse excisional wound model. Further studies showed that ectopic circ-Amotl1 increased protein levels of Stat3 and Dnmt3a. circ-Amotl1 not only increased Stat3 expression but also facilitated Stat3 nuclear translocation. the ectopic expressed circ-Amotl1 and Stat3 were mainly translocated to nucleus. In the presence of circ-Amotl1, Stat3 interacted with Dnmt3a promoter with increased affinity, facilitating Dnmt3a transcription. Ectopic application of circ-Amotl1 accelerating wound repair may shed light on skin wound healing clinically.	loss of function, gain of function	NIH 3T3, HGF	mouse model		Stat3	circRNA-protein		predicted	The molecular simulation result supports that circ-Amotl1 could perfectly dock Stat3 and predicts a minimal binding region of circ-Amotl1 for Stat3: ＆AACCTTCAC＊＆AAC＊＆AGGAAGAA＊. The contact map, the residue-level resolution contact maps (Figure S6C), the MC score, the contact distance, the accessible surface area, and the interaction overview all supported the conclusion that circ-Amotl1 sufficiently docked Stat3.		
mmu_circ_0001796	circRNA	mus musculus	Zfp609	mmu_circ_0001796	mm9_circ_017858		CAATGATGTTGTCCACTGGACATGTTCTGACCAAGGAGGCAGGTCTGAGAACGTAGCTGAAGCTGAAAATAGGAAAGCTGGGGGCAAGGAAGAGCCTTGAACCTTGAGGTGGGACGTTGACTCTAAGATGTCCTTGAGCAGTGGAGCCTGCGGAGGGAAAGGAGTGGATGCAAACCCGGTTGAGACATACGACAGTGGGGATGAATGGGACATTGGAGTAGGGAACCTCATCATCGACCTGGACGCCGATCTGGAAAAGGACCAGCAGAAACTGGAAATGTCAGGCTCCAAGGAGGTGGGGATACCAGCCCCCAATGCTGTGGCCACACTACCAGACAACATCAAGTTTGTCACCCCAGTGCCAGGTCCTCAAGGGAAGGAAGGCAAATCAAAATCCAAAAGGAGTAAGAGTGGCAAAGACGCTAGCAAGCCCACTCCAGGGACTTCCTTGTTCTCTCCAAGTGAGGGAGCAGCCAGCAAGAAAGAGGTGCAGGGTCGCGCAGGAGATGGTGCCAGTGCGGGAGGCCTGGTTGCTGCTGTTGCTCCCAAGGGCTCAGAGAAGGCTGCTAAGGCGTCACGCAGTGTAGCTGGCTCCAAAAAGGAAAAGGAGAACAGCTCATCTAAGGGCAAGAAGGAGAGAAGTGAAGGCGTGGGGACTTGTTCGGAAAAGGATCCTGGGGTCCTCCAGCCAGTTCCCTTGGGAGGACGGGGTAGTCAGTATGATGGAAGTGCAGGGATGGACACAGGAACCGTGGAGCCGCTTGGGAGTATAGCTATTGAACCTGGGGCAGCGCTCAATCCTTTGGGAACTAAGCCGGAGCCAGAGGAAGGGGAGAATGAGTGCCGGCCACTAAAGAAAGTCAAGTCTGAAAAGATGGAGTCCCCAGTCTCCACCCCAGCGGTGCTGCCACTGCACCTGTTAGTGCCAGTGGTCAATAATGACATCTCATCTCCCTGTGAGCAGATCATGGTCCGTACCCGATCAGTTGGTGTCAACACATGCGACGTGGCTCTAGCCACAGAGCCTGAGTGCTTAGGCCCCTGTGAGCCTGGAACCAGCGTCAACCTTGAAGGCATCGTGTGGCAGGAAACAGAAGATG	pulmonary toxicity induced by radon	29165116	Circular RNA profiles in mouse lung tissue induced by radon.	Pei W, Tao L, Zhang LW, Zhang S, Cao J, Jiao Y, Tong J, Nie J.	Environ Health Prev Med.  2017	The expressions of the circRNA was examined in mice of 60 WLM group.	microarray, qRT-PCR	BALB/c mice lung tissue												
circZfp609	circRNA	mus musculus	Zfp609	mmu_circ_0001797	mm9_circ_004501		CAATGATGTTGTCCACTGGACATGTTCTGACCAAGGAGGCAGGTCTGAGAACGTAGCTGAAGCTGAAAATAGGAAAGCTGGGGGCAAGGAAGAGCCTTGAACCTTGAGGTGGGACGTTGACTCTAAGATGTCCTTGAGCAGTGGAGCCTGCGGAGGGAAAGGAGTGGATGCAAACCCGGTTGAGACATACGACAGTGGGGATGAATGGGACATTGGAGTAGGGAACCTCATCATCGACCTGGACGCCGATCTGGAAAAGGACCAGCAGAAACTGGAAATGTCAGGCTCCAAGGAGGTGGGGATACCAGCCCCCAATGCTGTGGCCACACTACCAGACAACATCAAGTTTGTCACCCCAGTGCCAGGTCCTCAAGGGAAGGAAGGCAAATCAAAATCCAAAAGGAGTAAGAGTGGCAAAGACGCTAGCAAGCCCACTCCAGGGACTTCCTTGTTCTCTCCAAGTGAGGGAGCAGCCAGCAAGAAAGAGGTGCAGGGTCGCGCAGGAGATGGTGCCAGTGCGGGAGGCCTGGTTGCTGCTGTTGCTCCCAAGGGCTCAGAGAAGGCTGCTAAGGCGTCACGCAGTGTAGCTGGCTCCAAAAAGGAAAAGGAGAACAGCTCATCTAAGGGCAAGAAGGAGAGAAGTGAAGGCGTGGGGACTTGTTCGGAAAAGGATCCTGGGGTCCTCCAGCCAGTTCCCTTGGGAGGACGGGGTAGTCAGTATGATGGAAGTGCAGGGATGGACACAGGAACCGTGGAGCCGCTTGGGAGTATAGCTATTGAACCTGGGGCAGCGCTCAATCCTTTGGGAACTAAGCCGGAGCCAGAGGAAGGGGAGAATGAGTGCCGGCCACTAAAGAAAGTCAAGTCTGAAAAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	Some circRNAs showed even a reciprocal expression pattern during differentiation (such as circZfp609), which supports the previous finding that circularization can compete with linear splicing. Another example is circZfp609. Its mRNA is expressed on a constant level during neuronal differentiation, while the circRNA is highly upregulated in neurons.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
Cdr1as	circRNA	mus musculus	Cdr1	mmu_circ_0001878	CDR1as		GGTTTCCAGTGGTGCCAGTACCAAGGTCTTCCAACATCTCCAGGTCTTCCAGCAACTGCAAGTCTTCCAACACTGTCAAGGTCTTCCAGACAATCGTGATCTTCCAGAAAATATGTCTTCCAGATGATATATGTCTTCCAACAACCTCAGAGTCTTCCAGTAAATTCAGTCTTCCATGGTATCTAGATCTTCCGTGATATCTAGATCTTCTAGGAAAATCTGTGTCTTCCAGGAAAATCTTTGTCTTCCAAGGGATCCATGTCTTCCAGAAAAAAATCCACGTCTTCCAGAAAAATTCATGTCTTCCAGGAAAATCCATGTCTTCCAGAAAAATCCAAGTCTTCCAGAAGAATCTAAGTCTTCCTGAAAAATCCATGTCTTCCATAACAATCTACATCTTCCAGAATAATCAACGTCTTCCACAAAATTCAGGTCTTCCAGAAAAATATCCAGGTCTTCCAACCAGTCTATGTCTTCCAGAAAAATCCAGGTCTTCCAGCTCATCTATGTCTTCCATCAGTTCAAGTCTTCCAGATACCCATGTCTTCCATTAAATCTAGGTCTTCCAATAGATCTATGTCTTCCTGAAAATTAACGTCTTCCAATAATGTCCAAGTCTTCCAGCCAAGATATGTCTTCCTGAAGATTAATGTCTTCCTGAAGATTGACATCTTCCAGCAGAAAATCTTTGTCTTCCATTAAATCCACATCTTCCAGAAAATCCATGTCTTCCCAAAAATCCACATCTTCCAGGAAATCAACGTCTTCCCCAAAATCCATGTCTTCCTGAAAATCCACCGTCTTCCAAATAATCCAAGTCTTCCCAGAAATCGAAGTCTTCCCGAAAATCCATGTCTTCCCAAAAATCTACGTCTTCATGAAAATCTATGTCTTCCCAAAAATCCAAGTCTTCCCAGAAATCTAAGTCTTCCTGAAAATCCAAGTCTTCCCAAAAGTCCATGTCTTCCCAAAGATCCATGTCTTCCCGAAAATCCACGTCTTCTGGAAAATCGAAGTCTTCCCAGAAATCCAAGTCTTCTGGAAAATCGAAGTCTTCCCAGAAATCCAAGTCTTCCGGAAAATCGAAGTCTTCCCAGAAATCGAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCTGAAAATCCAAGTCTTCCTGAAAATCTAAGTCTTCCGGAAAATCTAAGTCTTCCAGAAAATCTACGTTTTCCCAGAAATCCAAGTCTTCCCAGAAATCCAAGTCTTCCCAGAAGTCCAAGTCTTCCTGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAGAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAGAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAGAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAGAAGTCCAAGTCTTCCCAGAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAGAAGTCCAAGTCTTCCCAGAAGTCCAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAGAAGTCCAAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAGTCCAAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAATCCAAGTCTTCCCAGAAGTCCAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAATCGAAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAAAAATCCAAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAATCCAAGTCTTCCCAGAAGTCCAAGTCTTCCCGAAAATCCAAGTCTTCCCGAAAATCCAAGTCTTCCCAGAAATCCAAGTCTTCCCAGAAGTCCGAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAATCCAAGTCTTCCCAGAAATCCGAGTCTTCCCAGAAGTCCAAGTCTTCCCAGAAGTCCAAGTCTTCCCAGAAATCCGAGTCTTCCCAAAGATCCACTTCTTCCCAGTAATCTGTGTCTTTCCAGAAATCCGTGTTTTCCCGAAAATCCAAGTCTTCCCGAAAATCAATGTCTTCCTGAAAATCCAAGTCTTCCCAGAAACCCATGTCTTCCTGAAAATCCATGACTTCCCAAAAATCCAAATCTTCCTGAAAAATCCATATCTTCCCAAAAATCCACGACTTCCCAAAAATCCATGTCTTCGTGAATATCCACGTCTTCCTGAAAATCCAAGTCTTCCCAGAAATCCATGTCCTTCCAAAAATCCATGTCTTCCTGAAAATCTATGCCTTCCATAAATCTACATCTTCCTGAAAATCCACATCTTCCTGAAAATCTACATCTTCCTGAAAATCCACATCTTCCATAAATCCCAGTCTTCCCAGAAATCCAAGTCTTCTGGAAAATCCATGTCTTCCTGAAAATCTATGCCTTCCACAAATCCATGTCCTCCTAACAATCCAAGTCTTCCTAAAAATCTACGCCTTCCACAAATCTACATCTTCCTGAAAATCCACATCTTCCCAAAATCCATGTCTTCGGAAAAAATCCATGTCTTCCAAGGAGTACATGTGTCTTCCTTCACCTCCAAGTCTTCCAGCATCTCCAGGGCTTCCAGCATCTGCCTGTCTTCCAACATCTCCACATCTTCCAGCATCTTTATGTCTTCCAACAACTGCGCAGTGTCTCCAGTGTATCGGCGTTTTGACATTCAGGTTTTCTGGTGTCTGCCGTATCCAG		25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	By northern blots, using probes detecting both linear and circular isoforms, we validated this circRNA to be specifically enriched in the brain, although its linear isoform mostly show much broader expression patterns across tissues.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circ-Zfp62	circRNA	mus musculus	Zfp62	mmu_circ_0003067			GAAGTTGAAATGGAAGGTCTAAAATTGAAAAGTAAATGGATGGAAAATCTGATATATGTGGACATGGCAGAGTATAGATAAGGTGAAGAAACTGCTGTACAAAGAAGTTAAATAGCTATCCCAAAGGTCATATAAGTAGGTATTTGAACCTAGTTGGTATTCTAGTCATTTTCTGGTCTGTGTGAGAGATTGGGTTTAATATTTCACAGATAGCAGAGTCCACTACAGAGGTTGGAGTTCCTTATTTAAAACAACAGTATTTACATATGACCTTTACACATCATCCTGTGTACTTGAAATTATTTTCAAATTACTTGCAGTGCCTAAAAGCAGTGTGAATCTTTATTTCGTTGTATTATTTAGAGAATAATGATAAACATTAAAAGCTGTATATGTTCAGCACAAATGTAACTTTGTTTTTCTGGTATTTTGGGTCCATGGTTGGCTGAATCTGTAAATGCAGAACCTGCCGCTGTGAAGGGCCAACTACTCTCCTCAGTGGCTTGAGGTGTTGCTGTCTTGTTTTAGCATCCGTGAGACAAAGATCTTATGCCATAGTTCAGGCTGGCCTGGAACATGCAGTAACCTTCCTGCCTCAGCCTCCAAAGTGCAAGAATAATAAGATTGAGCCATTACACTTTGCTATTTGTAAGCTTTGACATTCTATATGACTAATTGATTCATAAATAGGAATGAAAACTTTATTCCTTGGCAGGCTGGAGCATGTTTCTACCATGTAAGTTCTTCCATGATTAGCCACTTTCCAAAGAGTGTTTTCCTTACACAGAAAAGTCAAGAAGGCCAAATTACGGTATAGTAGCTTTAGGTTTCTTTGTTTCTCATTTCTTGGTCACTGTCCTCATCATCTTATAACTGCAACTCCCTGCCTGATTCCTCTTCTACGGTCCTGACTTATCTTCCTTTTCAGTTTTTCCTGCTCTCTCCTGATTATGTGTAACTTTTCAAAGAAAAAATTAACATCTTTGTTGTTCTAACTTTTTTCTGTCATGTTTTTCAGAGACTTCTTTTTTCTTGTTTTTCTATGAGGTGACATTGAAACTGATTGGTATTGGCTGTGGTTTTGTGCATCAGTTGAACCCATTTTTATGGTACCTTCTGGACTCTTGTTTTAACAGTAGTTCTAAAGGTATTGAAATCTTATTAATGTCCCCCATCATAATTCCAGTAATTAAAATGGTACTGGAAGGGCTGGAGAGATGACTTAGCAGTTAAGAGCATTTGATGCTCTTGCAGAGGACCTGGGTCCAGTTCCCAACACCCTATGATCACACCCAACCATCCATGCTAACTCCAGTTCCAGAGGGATCTGACTACCTCTTCTGAACTCAATGGGCACCAGACATGTGCATGGTGCACATTCCTCCAAGAAAGCAAAAACACTCAAAAAAATTTAAAGATTATTTTTTAAATGGTACCTGCCACATATTAAAAAGCAAATATCTGACAAATGGATAAGTTAATTTTGTTATTTGCTGTTGTTACTCATTCAGGGTTTTTTCCTAAATAAACATGTCATTTTCATTCTTTTGGTCTAGTGTCATATTTGAAGACAACCATGGAGGATGAGGAGTCGTCTAAAAAGAATGAAAATGATTCAAATGCAGACTCTCAGTGCCCAAGTGTGGGATTTTTTCATAAGGATCATATGCAGAAATCTAAGACCGGTGACACTTGTGACTTGTTTCCTAAATGGAAAATACTGAAGGAAGGCAAAAGTAGTATCAGAGAAATGATTGACACACATACAAACGCAGCAAATATAAAACTAGAGCAGGATGATGAGACATCTGAGAAAAGTTTCTACCCAAGTACAAATACAATGCACCAGACTATCCCCACAGAACCAAATTGTACTAAACAAGGTGAGCACACAGAGAACATTAATGGAAACGTACACCCTGCTCATATTGCTGATAAGAAATTACATAAGTGTGATGAGTGTGGAAAATCCTTCAAATACAATTCTCGTCTTGTTCAACATAAAATTATGCACACTGGAGAAAAGCGCTACGAGTGTGATGACTGTAGGGGGACTTTTCGGAGTAGCTCCAGTCTTCGAGTCCACAAGCGCATCCATACTGGGGAAAAGCCCTATAAGTGTGATGAGTGTGGCAAAGCCTACATGTCCTACTCTAGCCTTATAAACCACAAAAGCACTCATTCTGGGGAGAAGAACTGCAAATGTGACGAATGTGGAAAATCCTTCAATTATAGTTCTGTTCTGGACCAGCATAAAAGGATCCACACCGGAGAGAAGCCCTATGAATGTG	aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Significantly increased at 6 mo compared to 1 mo.	RNA-seq, qRT-PCR	22 mo cortex, 6 mo cortex, 1 mo cortex												
circ-Onecut2	circRNA	mus musculus	Onecut2	mmu_circ_0007448			CATGCAAACGCAAAGAGCAAGAACCAAACAAAGACAGGAACAACTCGCAGAAGAAATCCCGCCTGGTGTTCACGGACCTCCAACGCCGAACACTCTTCGCCATCTTCAAGGAAAATAAGCGCCCTTCGAAGGAGATGCAGATCACCATTTCCCAGCAACTTGGGCTGGAGCTGACCACTGTCAGTAACTTCTTCATGAATGCCCGGCGTCGCAGCCTGGAGAAATGGCAAGATGACCTAGGCACAGGGGGTTCTTCATCCACCTCCAGCACTTGTACCAAAGCATGATGCAAGGACTCTCCACCTGGGCACAAGTCATCTCCAAATGAGGACAACACATACCAAAAACCAAAACCAAAAACCAAAACCAAAACCAAAACCAAAACCAAAACCAAAAAAAAAAAAAAAAAAAAATCACAAAGACATCAGATTCTTAGCTGGGGCCCTTCACTGGTGACTTGAAAGCACAATTCTCTTGAAACTTCTAATCTAGCTGTAATCATAGGCCAGGTGTCCATTTTCTTTTGTTTCATTTTAAATGGCTACAGAGTCCAAGTACACGCTGAAAGTTAATCTCTTTGAACCAGACACTATCCTCTGAGTATGCTAAGCATCCCAGAGACCCAAATGGGGCCTTCTTGGAGTGAGTTAATCACAGCACAATGTCAACCAAGTTCAGTGCAGCTGTAAGCATCAATAGCCCTATTCAGGCCCTGTCAACCTCTTGCTAACACTAGTTTCCTGCAAGTCATAGTGGATATTTGGCCTGAGTATAGACACAGGATTCCAAAACACTACAGAAGAATTTAACAAGAAAGGCCTCATTTGCTCCCCAAGTGCTTAGCCTCTTTATATCACAGTACATTAAAAATTCTCAGCCATAACATTACAAAAAAAAATCAGAATGGTAATTACTGAGCACAAGTTTTAAATATGGAAATCAATAAAAAAAATCCAAGGACATGTTTTTCCAACTCAGGCATCTTTTCATTGGATAGTTTAGAAAACTTTGATTTCAGTTTACGATTTTTCTTTTCTTTACCTCCTGGAAATCTCATGTGGTCTTCTGGATCCGTCAAAAAAAAGTCAATTCACTTGAGCTCAAAGTATCAAGCACAACGAAGATATACAGAAATAAGGAAGGCTCTGGTTTCAACGCATCCAGTTTGACAAGGCCGTTTACATCAGTCTTTACTGTTGTGAAGTCATTAGGGAATTATTGGGAATATGGCTTCAAGCACATTTTGCAGGTTGTTACAAACTCTGTTTGTACATTGCGCAGATGCACACTCAGGAGGCCAATTTAACTGCTACAGTACAGGAGCAAATGCATCATTTAAGAAGATCTAGATTTTTTTAGATCATTACTGTGCCCTTGATTTACAAGTCACCCAGGTCCTCCTATGTGCATTACAAGTGTGGTTTGTTCTTGTTCTTGCTGATCCGTGTTGTTCCCTATCGCATCCCATTAGTTGGGATGTCTCTATTGTTTTCTACAAAGAAACAGTTTAATAAGCCACTTCCTGTCGTCTCTTCCTAACTCTCTTCCATTGCTGATTCATCCTTATAATACAGCTGACAGAACCTGGAGAGAACACAGCACACCAAAGAAGCAGAATACTGCAAACCAAAGACATTTGTTACCTGCCATTTTCTAGCCTACAAATACTGTGATTACTTTTAGAGATCAGAGCACCTCTGTAACTCCGAGTGGCATTCGGCTCTTGTCTTGGGCTCACCACCTGGCTGAGCAGACCAGCTACATCAATGACATTAGCCAAATATCCGGGCAGTGACTTCGCCACGCCAGCCCTGGTTGGTCACCTTCCCATAGCAAGTGAAAGAGGGCCCACAGAACTCTGGGAGATTACAAAGGTCACTATGTGCATATTTACCAGTGAATGGCCCCAGGTGGGCACCAAGGGGTGTTCGGAGCAAGCCAAAAGCTTCGATGACTCTTTACAGACACTTGAGACTGACTTTTGTATGAATTGCTTAATTGAAACCAAAGAAACTTTTTTTCTGCACCTACTTCTGCAACAAACAGAACTGTCCCATTGAATGAGTAAATGGTTCCACCAATCACTGGAAATCACCATCAACAGAAAAAGCACGCTAGAATGAAAGAAACAACAAAACCACCGAAGACACACTGTGTTCAAACAGACCTTTTGGGACGCTCTTATTTTTTATTTTTTTATTTTTTGGAAGCAGATTTGAAAGAAAGGGTTGAGACACAAATCAACAGACGAGCCTCAATGGCTGCTGCTTCATATGACAACTCACTCGGTAATCTTAACGTTGAAGATTGTCTTTAATTTGTGCCTATGCAGTTTTTCAAAAGAACATGGAAACAGAGCAACAGAAACCTCAACAGCTACAATACCAAAGATGAGGATTCTCACACCTTTTTGTCTCAGTTCATTACCTTCTTTTGCCTGGCTAAAATACTTATAGCGTCATTGATCTGTACAAAG	aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Significantly increased at 6 mo compared to 1 mo.	RNA-seq, qRT-PCR	22 mo cortex, 6 mo cortex, 1 mo cortex												
circ-Fmn2	circRNA	mus musculus	Fmn2	mmu_circ_0008444			CAAGATCAGCTTTACACCTGGGCTGCGGTTAGTCAACCCACACATTCGATGGATTACAGCGAAGGGCAGTTTCCCAGGAGAGAACCATCTATGTGGCCATCATCCAAGCTTCCTGAGGAAGAGCCCAGTCCCAAGGACGTTGATACAGAACCTAAATCCTCTATTTTGGAAAGCCCGAAAAAATGCTCAAATGGTGTCCAGCAGGAAGTTTTCGATGTGAAGTCTGAAGGACAGGCAACTGTAATTCAGCAACTGGAACAGACCATCGAGGATCTACGCACAAAAATAGCTGAGCTAGAGAAGCAATATCCAGCCCTGGACTTGGAGGGACCCAGAGGCCTCTCAGGACTTGAGAATGGATTGACAGCCTCTGCAGACGTCAGTCTAGATGCTCTTGTATTGCATGGGAAGGTTGCACAGCCTCCAAGGACTCTTGAGGCAAAATCAATACAGACTTCCCCAACAGAAGAAGGTAGAATCCTGACATTGCCACCTCCAAAGGCACCACCAGAGGGTCTTCTGGGGTCCCCTGCAGCTGCAAGTGGAGAGTCAGCCCTTCTAACCTCACCCTCTGGACCTCAGACAAAATTCTGTTCAGAGATTTCTCTGATTGTGTCTCCAAGGAGAATATCAGTACAGCTGGATGCCCAACAGATACAGAGTGCATCACAACTACCACCACCTCCTCCTCTCCTTGGGTCTGATAGTCAGGGACAGCCCTCCCAACCTTCTCTGCATACTGAGTCAGAAACCAGCCATGAACATTCTGTTTCCTCCTCCTTTGGAAACAACTGTAATGTCCCACCCGCACCACCTCTGCCTTGTACAGAGTCCTCCAGTTTCATGCCTGGCCTGGGCATGGCAATTCCCCCACCTCCCTGTCTCTCTGACATAACAGTGCCTGCTCTGCCCAGTCCTACAGCCCCAGCCCTACAATTTAGCAATCTACAGGGACCAGAAATGCTGCCAGCCCCTCCCCAACCTCCTCCTCTTCCTGGGCTAGGAGTACCCCCTCCTCCCCCTGCCCCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATACCTCCCCCACCTCCTCTCCCTGGAATGGGAATATCTCCCCTACCTCCTCTCCCTGGAATGGGAATACCTCCTCCCCCTCCTCTACCTGGAGTGGGCATACCCCCTCCTCCTCCTCTTCCTGGAGTGGGCATACCCCCTCCTCCTCCTCTTCCTGGAGTGGGAATACCCCCTCCTCCTCCTCTTCCTGGAGTGGGAATACCTCCTCCCCCTCCTTTACCTGGAGTGGGAATACCCCCTCCTCCTCCTCTTCCTGGAGTGGGCATACCCCCTCCTCCTCCTCTTCCTGGAGTGGGAATACCCCCACCCCCTCCACTTCCAGGAGTGGGAATACCCCCTCCCCCTCCTTTACCTGGATCAGGCATACCCCCTCCTCCTGCTCTACCTGGAGTTGCTATTCCTCCACCACCTCCTCTACCAGGTATGGGGGTTCCACCTCCCGCCCCACCTCCCCCTGGGGCAGGCATCCCCCCACCCCCACTGTTGCCTGGCTCAGGTCCTCCACACTCCTCACAAGTTGGGAGTAGCACTTTACCAGCAGCACCTCAAGGGTGTGGATTTCTTTTTCCTCCATTGCCCACTGGCTTGTTTGGATTAGGGATGAATCAGGACAGAGTGGCTAGGAAGCAGCTGATCGAGCCTTGCCGGCCAATGAAGCCTCTCTATTGGACAAGAATTCAACTCCATAGTAAAAGAGACTCCAGCCCTTCGCTTATTTGGGAAAAGATTGAAGAGCCATCCATAGACTGTCATGAATTTGAAGAATTATTTTCTAAAACTGCAGTAAAGGAGAGAAAGAAACCTATTTCTGACACAATTTCAAAGACAAAGGCCAAACAA	aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Significantly increased at 6 mo compared to 1 mo.	RNA-seq, qRT-PCR	22 mo cortex, 6 mo cortex, 1 mo cortex												
circ-Pclo	circRNA	mus musculus	Pclo	mmu_circ_0012310			ATCAAAGAGTGGCTCTGTTTAAACTGTCAGATGCAAAGAGCTCTGGGAGGTGAACTGGCAGCAATCCCATCCTCACCGCAGCCAACCCCAAAGGCTGCCTCAGTACAGCCAGCAACAGCCAGCAAATCACCTGTACCGTCACAGCAGGCTTCCCCAAAGAAGGAACTTCCATCCAAACAGGACAGCCCCAAAGCACCGGAGTCCAAAAAGCCACCGCCACTGGTGAAACAGCCAACCCTTCATGGACCTACCCCGGCTACAGCCCCACAGCCTCCAGTGGCAGAGGCCTTACCTAAGCCAGCCCCTCCCAAGAAGCCTTCTGCAGCCCTACCTGAACAAGCAAAGGCCCCTGTTGCAGATGTTGAACCAAAGCAACCGAAGACGACAGAGACACTCACAGATAGCCCATCTTCAGCAGCAGCAACCTCAAAGCCTGCTATTCTGAGCTCTCAAGTGCAGGCACAGGCTCAAGTGACAACGGCCCCTCCTTTGAAAACAGACTCTGCCAAAACTTCACAGAGTTTCCCACCAACAGGAGATACAATTACCCCACTTGATTCTAAAGCCATGCCCAGGCCTGCATCAGACTCAAAAATTGTTTCACATCCTGGGCCCACTTCTGAGAGCAAGGATCCAGTTCAGAAGAAGGAGGAGCCTAAGAAAGCACAAACCAAGGTGACCCCTAAACCAGATACAAAGCCAGTACCAAAAGGATCCCCAACACCGTCTGGCACACGACCTACGACTGGCCAAGCCACACCCCAGTCTCAGCAGCCCCCGAAGCCTCCGGAGCAGTCAAGACGGTTCAGTTTGAATCTGGGGGGTATCGCTGATGCCCCCAAATCACAGCCCACAACTCCTCAAGAAACTGTGACAGGGAAGCTATTCGGGTTCGGAGCATCCATCTTTAGCCAAGCATCAAACTTAATTTCCACAGCAGGTCAGCAAGCACCTCATCCACAGACTGGGCCAGCTGCCCCATCAAAGCAAGCCCCTCCCCCATCCCAGACTCTGGCTGCTCAGGGACCACCCAAGTCCACAGGTCCGCACCCATCAGCACCTGCCAAGACGACTGCTGTGAAGAAGGAAACAAAAGGCCCGGCAGCTGAAAACTTAGAGGCCAAACCTGTGCAAGCTCCAACAGTGAAGAAGGCAGAGAAAGACAAGAAGCCCCCACCTGGGAAGGTCAGCAAACCTCCACCTACAGAGCCCGAGAAGGCCGTCCTCGCCCAGAAGCCAGACAAGACCACCAAACCCAAACCGGCCTGTCCTCTCTGCAGAACGGAACTCAACGTAGGGTCTCAGGATCCTCCCAACTTCAACACCTGCACAGAATGCAAGAATCAAGTTTGCAATCTCTGTGGATTTAACCCAACGCCCCACCTGACTGAG	aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Significantly increased at 6 mo compared to 1 mo.	RNA-seq, qRT-PCR	22 mo cortex, 6 mo cortex, 1 mo cortex												
circ-Kdm3a	circRNA	mus musculus	Kdm3a	mmu_circ_0013507			CCCCAGCCCGGAAGTCAGTTTTGACAGACCCAGATAAAGTCAGGAAGCTGCAGCAGAGCGGAGAGGCCTTTGTTCAGGATGACTCCTGTGTTAACATCGTGGCACAGCTGCCCAAGTGTCGGGAGTGTCGACTAGACAGCCTGCGCAAGGATAAGGACCAGCAGAAGGACTCTCCTGTGTTTTGTCGCTTTTTCCACTTCAGGAGATTACAATTCAACAAGCATGGTGTGTTGCGGGTAGAAGGCTTCTTAACACCAAACAAGTATGACAGTGAAGCGATTGGCTTGTGGCTGCCTTTGACCAAAAATGTTGTGGGGACTGATTTGGACACAGCAAAATATATCCTGGCCAATATTGGAGACCACTTCTGTCAAATGGTGATTTCTGAGAAGGAAGCTATGTCGACTATTGAGCCACACAGACAGGTTGCTTGGAAACGAGCTGTCAAAGGAGTTAGAGAAATGTGTGATGTGTGTGACACAACCATTTTCAACCTGCACTGGGTGTGCCCTCGGTGTGGGTTTGGAGTATGTGTAGATTGCTACCGGATGAAGAGGAAGAACTGCCAACAGGGTGCTGCCTACAAGACTTTCTCTTGGATAAGGTGTGTGAAGAGTCAGATACATGAGCCTGAGAACCTGATGCCCACACAGATTATTCCTGGCAAAGCCCTCTACGATGTTGGAGACATTGTGCATTCTGTCAGAGCAAAATGGGGCATAAAGGCCAATTGTCCCTGCTCCAACAGGCAGTTCAAGCTCTTCTCAAAGCCAGCCTTAAAGGAAGACCTGAAACAGACATCCTTGTCTGGAGAAAAACCAACTCTTGGGACCATGGTCCAGCAAAGTTCCCCTGTTTTGGAGCCAGTGGCTGTGTGCGGGGAAGCAGCCTCCAAGCCAGCCAGCAGCGTGAAGCCCACCTGTCCCACCAGCACTTCACCTTTAAACTGGCTAGCTGACCTTACCAGTGGGAATGTCAACAAGGAGAATAAGG	aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Significantly increased at 6 mo compared to 1 mo.	RNA-seq, qRT-PCR	22 mo cortex, 6 mo cortex, 1 mo cortex												
circ-Cwf19l2	circRNA	mus musculus	Cwf19l2	mmu_circ_0015534			TCCAGAGGCAGAGTCCACCTATATCTTAAATGTTGATGAAAAGAACAAGTTGGGGGCCAAGATTATCAAGGCAGAAATGATGGGGAATATGGAATTAGCTGAACAACTTAAAGCCCAACTTAAAGAGGCAAATAAATTTAAAGAAACACAGATGCCGGCAAAAAGATTGGGCGTAGAGCATGAAGATGAACAAGAAGTAATCCTTATTCAAACAGATAAGTCTGGAAGAATGTGGCCTGTGAGCAGCCCTAGAGAAACCCTGGATATGAAAGCAGAACGAAGGAAGAGAAAGAGAGTTTCAACCCATGAGGATAAAGAAAGGGTCCGATACTTTCCTGATGATGATCATTTGAGCCTCAAAGATTTAGTCAAGAATGAGAAAATAGGAACAGATATCAACCAAAACAGACTTTTCATGAAAATGGCATCTAAGTTTATGGGAAAATCAGATGAAGACAATTATACTCTGGATGACATGTTTGTCTCCAAAGCAGCTGAGAAAGAGCATCTTGGTAAGAAGGAAGAGAGCCAGAGGAGAAGAGCGATTGCTGAGCACCAGAGTCTTGCTGCAAAAATGGCAAAGTGCCTTTACTGTTTTGACAGCTCTCAGTTCCCCAAGCACCTTATTGTTGCAATCGGTGTGAAGGTTTATTTATGTTTACCCAGTTTCCAGTCTCTTACTGAAGGACACTGCTTCATAGTCCCTCTGCAACATCATCAAGCAGCCACTGTATTAGATGAAGATGTCTGGGAGGAGATCCAGATGTTTCGAAAATCATTGGTAAAAATGTTTGAAGATAAAGAATTGGATTGTATCTTTTTGGAGACTAATATGGGTTTGAAGAAACACTATCATATGGTTTATGAGTGTATCCCTCTCCCAAAGGAAGTGGGTGATATGGCTCCCATCTATTTTAAGAAAGCCATAATGGAATCTGATGAAGAATGGTCCATGAATAAGAAGTTGATTGATTTGTCTTCAAAAGATATTAGAAAGTCT	aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	significantly increased between 6 mo and 22 mo hippocampus. 	RNA-seq, qRT-PCR	22 mo hippocampus, 6 mo hippocampus, 1 mo hippocampus.												
heart-related circRNA (HRCR)	circRNA	mus musculus						cardiac hypertrophy and heart failure	26802132	A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223.	Wang K, Long B, Liu F, Wang JX, Liu CY, Zhao B, Zhou LY, Sun T, Wang M, Yu T, Gong Y, Liu J, Dong YH, Li N, Li PF.	Eur Heart J.  2016	expressed in cardiomyocytes and mouse heart	qRT-PCR, northern blots, FISH	adult male C57BL/6 mice (8每10weeks old), cardiomyocytes	acts as an endogenous miR-223 sponge to inhibit cardiac hypertrophy and heart failure	gain of function	cardiomyocytes	adult male C57BL/6 mice (8每10weeks old)		miR-223	circRNA-miRNA	mouse heart	AGO2 IP, RNA pull-down, FISH	Fluorescence in situ hybridization (FISH) revealed that there is a co-localization between HRCR and miR-223 in cytoplasm. HRCR could pull down miR-223. HRCR pull down by AGO2 was specifically enriched in miR-223-transfected cells but not miR-223 mutant-transfected cells.	ARC	
mmu_circRNA_007893	circRNA	mus musculus							29039515	Calcitonin gene-related peptide induces IL-6  expression in RAW264.7 macrophages mediated by mmu_circRNA_007893.	Deng T, Yang L, Zheng Z, Li Y, Ren W, Wu C, Guo L.	Mol Med Rep.  2017	mmu_circRNA_007893 expression increased stably by ~2 fold relative to the control group. The data was in accordance with the results in the circRNAs microarray. mmu_circRNA_007893 were located mainly in the cytoplasm.	microarray, qRT-PCR, FISH	RAW264.7 macrophages	Silencing of mmu_circRNA_007893, IL 6 mRNA expression was significantly decreased, whereas mmu miR 485 5p expression was markedly increased. Furthermore, when overexpression of mmu miR 485 5p, IL 6 mRNA was markedly decreased. The results demonstrated that CGRP induced IL 6 mRNA expression was mediated by mmu_circRNA_007893, and mmu_circRNA_007893 functioned as an endogenous mmu miR 485 5p sponge as part of induction of IL 6 mRNA expression.	loss of function	RAW264.7 macrophages			mmu miR 485 5p	circRNA-miRNA	RAW264.7 macrophages	expression, qRT-PCR	mmu_circRNA_007893 regulates IL 6 mRNA expression by mediating the level of mmu miR 485 5p.	IL-6	
circRar1	circRNA	mus musculus	Rar1					lead induced neuronal cell apoptosis	27604105	A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis.	Nan A, Chen L, Zhang N, Liu Z, Yang T, Wang Z, Yang C, Jiang Y.	Arch Toxicol.  2017	markedly upregulated in the hippocampus. upregulated in lead-treated N2a mouse nerve cells.	qRT-PCR	mouse cerebellum, pons, medulla oblongata, hippocampus and cerebral cortex. lead-treated N2a mouse nerve cells	circRar1 promote apoptosis in lead induced neurotoxicity	loss of function, gain of function	lead-treated N2a mouse nerve cells			miR 671	circRNA-miRNA	lead-treated N2a mouse nerve cells	FISH,luciferase reporter assay	These results indicate that lncRpa and circRar1 interact directly and specifically with miR-671.	Akt2, caspase8, and p38	
circRNA_010567	circRNA	mus musculus						myocardial fibrosis	28412345	A novel identified circular RNA, circRNA_010567, promotes myocardial fibrosis via suppressing miR-141 by targeting TGF-帣1.	Zhou B, Yu JW.	Biochem Biophys Res Commun.  2017	circRNA_010567 was markedly increased in diabetic mouse myocardium. CircRNA_010567 expression was confirmed in mouse myocardium using qRT-PCR, which showed circRNA_010567 was significantly up-regulated in myocardium.	microarray, qRT-PCR	diabetic mouse myocardium	Functional experiments revealed circRNA_010567 silencing could up-regulate miR-141 and down-regulate TGF-b1 expression, and suppress fibrosis associated protein resection in CFs, including Col I, Col III and a-SMA. Results demonstrate the circRNA_010567/miR-141/TGF-b1 axis plays an important regulatory role in the diabetic mice myocardial fibrosis model.	loss of function	mouse cardiac fibroblasts			miR-141	circRNA-miRNA	db/db diabetic mice myocardium	luciferase report assay	circRNA_010567 directly targeted miR-141 and mediate it negatively.	TGF-beta1	
circRNA_Atp9b	circRNA	mus musculus	Atp9b				TTGGCAGTCTGCGAGTAAACTTGGATATGGGCAAAGCAGCATATGGATGGATGATTATGAAAGATGAGAATATTCCTGGTACAGTTGTTCGGACCAGCACAATACCAGAAGAACTTGGACGCCTGGTGTACTTACTGACAGACAAAACAG*GTAAAGTTCAAGTTAAGAGCTCAGACATACAAGTTGGAGACCTCATCATAGTGGAAAAGGTTGATACATTTTTTTAATATATTTTAAATCTGTATGTTCAACAGTCATTAACATTAGCTTAATTACAAGTAACGTTAACTTCAAATGAAC	osteoarthritis	29305974	Circular RNA Atp9b, a competing endogenous RNA, regulates the progression of osteoarthritis by targeting miR-138-5p.	Zhou ZB, Du D, Huang GX, Chen A, Zhu L.	Gene.  2018	Compared with the normal control group, circRNA_Atp9b expression levels were significantly up-regulated in IL-1汕-induced chondrocytes in a time-dependent manner.	qRT-PCR	chondrocytes	Knockdown of circRNA_Atp9b promoted the expression of type II collagen while inhibiting the generation of MMP13, COX-2 and IL-6. circRNA_Atp9b regulates OA progression by modulating ECM catabolism and inflammation in chondrocytes via sponging miR-138-5p.	loss of function	chondrocytes			miR-138-5p	circRNA-miRNA	chondrocytes	luciferase reporter assay	these results illustrate that circRNA_Atp9b directly targets miR-138-5p by functioning as sponge.		
Cdr1as	circRNA	mus musculus	Cdr1					neuropsychiatric disorders	28798046	Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function.	Piwecka M, Gla鱉ar P, Hernandez-Miranda LR, Memczak S, Wolf SA, Rybak-Wolf A, Filipchyk A, Klironomos F, Cerda Jara CA, Fenske P, Trimbuch T, Zywitza V, Plass M, Schreyer L, Ayoub S, Kocks C, K羹hn R, Rosenmund C, Birchmeier C, Rajewsky N.	Science.  2017	Cdr1as was highly expressed in neurons but not expressed in glial cells such as oligodendrocytes and astrocytes. Cdr1as was predominantly expressed in excitatory neurons. In the cerebellum, Cdr1as expression was observed exclusively in the granular layer with a high content of excitatory neurons and did not overlap with GABAergic neurons present in the molecular layer and Purkinje cells. Single molecule RNA FISH in primary cortical neurons revealed Cdr1as expression in both soma and neurites.	FISH	neurons, glial cells such as oligodendrocytes and astrocytes, excitatory neurons, cerebellum, soma and neurites.	When the Cdr1as locus was removed from the mouse genome, knockout animals displayed impaired sensorimotor gating〞a deficit in the ability to filter out unnecessary information〞which is associated with neuropsychiatric disorders. Electrophysiological recordings revealed dysfunctional synaptic transmission. Expression of miR-7 and miR-671 was specifically and posttranscriptionally misregulated in all brain regions analyzed. Expression of immediate early genes such as Fos, a direct miR-7 target, was enhanced in Cdr1as-deficient brains, providing a possible molecular link to the behavioral phenotype.	loss of function		Cdr1as loss-of-function mutant mice		miR-7 and miR-671	circRNA-miRNA	cerebellum, cortex, hippocampus, and olfactory bulb	Northern blots, FISH, and chromogenic ISH	there is a highly specific, posttranscriptional deregulation of miR-7 and miR-671 in the brains of Cdr1as KO animals. These are the two miRNAs that we identified by in vivo chimera analysis as directly interacting with Cdr1as.	Fos	
circRNA.36866	circRNA	mus musculus						Osteoarthritis	29247798	Circular RNA expression profile of articular chondrocytes in an IL-1帣-induced mouse model of osteoarthritis.	Zhou Z, Du D, Chen A, Zhu L.	Gene.  2018	Up-regulated in IL-1汕-induced mouse articular chondrocytes compared to controls.	RNA-seq, qRT-PCR	IL-1汕-induced mouse articular chondrocytes, controls						mmu-miR-5124b, mmu-miR-6361, mmu-miR-3473b, mmu-miR-3473e, mmu-miR-6369	circRNA-miRNA		predicted			
circRNA.30365	circRNA	mus musculus						Osteoarthritis	29247798	Circular RNA expression profile of articular chondrocytes in an IL-1帣-induced mouse model of osteoarthritis.	Zhou Z, Du D, Chen A, Zhu L.	Gene.  2018	Down-regulated in IL-1汕-induced mouse articular chondrocytes compared to controls.	RNA-seq, qRT-PCR	IL-1汕-induced mouse articular chondrocytes, controls						mmu-miR-7216-5p, mmu-miR-6238, mmu-miR-7094b-2-5p, mmu-miR-665-5p, mmu-miR-6769b-5p	circRNA-miRNA		predicted			
mmu_circRNA_40001	circRNA	mus musculus						focal cerebral ischemia	29156814	Screening circular RNA expression patterns following focal cerebral ischemia in mice.	Liu C, Zhang C, Yang J, Geng X, Du H, Ji X, Zhao H.	Oncotarget.  2017	Significantly upregulated in in the ischemic group	microarray, qRT-PCR	ischemic mouse brain, controls						mmumiR-466f, mmu-miR-466i-5p, mmu-miR-669n, mmumiR-1187, and mmu-miR-466c-5p	circRNA-miRNA		predicted			
mmu_circRNA_013120	circRNA	mus musculus						focal cerebral ischemia	29156814	Screening circular RNA expression patterns following focal cerebral ischemia in mice.	Liu C, Zhang C, Yang J, Geng X, Du H, Ji X, Zhao H.	Oncotarget.  2017	Significantly upregulated in in the ischemic group	microarray, qRT-PCR	ischemic mouse brain, controls						mmu-miR-6541, mmu-miR-669c-3p,mmu-miR-466f-5p, mmu-miR-669m-5p, and mmu-miR-466j	circRNA-miRNA		predicted			
mmu_circRNA_40806	circRNA	mus musculus						focal cerebral ischemia	29156814	Screening circular RNA expression patterns following focal cerebral ischemia in mice.	Liu C, Zhang C, Yang J, Geng X, Du H, Ji X, Zhao H.	Oncotarget.  2017	Significantly downregulated in in the ischemic group	microarray, qRT-PCR	ischemic mouse brain, controls						mmu-miR-7038-3p, mmu-miR-20a-3p, mmu-miR-145a-3p, mmu-miR-346-3p, and mmu-miR-149-5p	circRNA-miRNA		predicted			
ciRS-7	circRNA	mus musculus	Cdr1		Cdr1as				26211738	The circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells.	Xu H, Guo S, Li W, Yu P.	Sci Rep.  2015	Cdr1as was found to express in MIN6 cells, mouse islets, brain, pituitary gland and AtT-20 cells. expressed in islet cells and was upregulated by long-term forskolin and PMA stimulation.	qRT-PCR, sanger sequencing	MIN6 cells, mouse islets, brain, pituitary gland and AtT-20 cells.	Cdr1as increased insulin secretion. Both insulin content and secretion were significantly increased by overexpression of Cdr1as in islet cells.	gain of function	MIN6, AtT-20		Mouse islets	miR-7	circRNA-miRNA	MIN6, islets	qRT-PCR	Cdr1as upregulates miR-7 target genes expression.	Myrip, Pax6	
circ-Atxn7	circRNA	mus musculus	Atxn7					cardiovascular diseases	28676412	Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.	Siede D, Rapti K, Gorska AA, Katus HA, Altm羹ller J, Boeckel JN, Meder B, Maack C, V繹lkers M, M羹ller OJ, Backs J, Dieterich C.	J Mol Cell Cardiol.  2017									ribosomes	circRNA-protein	mouse cardiac myocytes	RIP	Figure 4C shows a cluster of 4 circular RNAs (Myocd, Slc8a1, Atxn7 and Phf21a) where we see an enrichment of BSJ reads (column 1-4) over linear spliced reads (column 5-8) in the ribosomal IP fraction (column 1-2 and 5-8).		
circ-Myocd	circRNA	mus musculus	Myocd					cardiovascular diseases	28676412	Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.	Siede D, Rapti K, Gorska AA, Katus HA, Altm羹ller J, Boeckel JN, Meder B, Maack C, V繹lkers M, M羹ller OJ, Backs J, Dieterich C.	J Mol Cell Cardiol.  2017									ribosomes	circRNA-protein	mouse cardiac myocytes	RIP	Figure 4C shows a cluster of 4 circular RNAs (Myocd, Slc8a1, Atxn7 and Phf21a) where we see an enrichment of BSJ reads (column 1-4) over linear spliced reads (column 5-8) in the ribosomal IP fraction (column 1-2 and 5-6).		
circ-Phf21a	circRNA	mus musculus	Phf21a					cardiovascular diseases	28676412	Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.	Siede D, Rapti K, Gorska AA, Katus HA, Altm羹ller J, Boeckel JN, Meder B, Maack C, V繹lkers M, M羹ller OJ, Backs J, Dieterich C.	J Mol Cell Cardiol.  2017									ribosomes	circRNA-protein	mouse cardiac myocytes	RIP	Figure 4C shows a cluster of 4 circular RNAs (Myocd, Slc8a1, Atxn7 and Phf21a) where we see an enrichment of BSJ reads (column 1-4) over linear spliced reads (column 5-8) in the ribosomal IP fraction (column 1-2 and 5-9).		
circ-Slc8a1	circRNA	mus musculus	Slc8a1					cardiovascular diseases	28676412	Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.	Siede D, Rapti K, Gorska AA, Katus HA, Altm羹ller J, Boeckel JN, Meder B, Maack C, V繹lkers M, M羹ller OJ, Backs J, Dieterich C.	J Mol Cell Cardiol.  2017									ribosomes	circRNA-protein	mouse cardiac myocytes	RIP	Figure 4C shows a cluster of 4 circular RNAs (Myocd, Slc8a1, Atxn7 and Phf21a) where we see an enrichment of BSJ reads (column 1-4) over linear spliced reads (column 5-8) in the ribosomal IP fraction (column 1-2 and 5-7).		
circ-Foxo3	circRNA	mus musculus	Foxo3						26861625	Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2.	Du WW, Yang W, Liu E, Yang Z, Dhaliwal P, Yang BB.	Nucleic Acids Res.  2016	highly expressed in non-cancer cells	qRT-PCR, northern blots	MEF, MCF, NIH3T3, 67NR, 66C14, 4T07, 4T1 and B16	Silencing endogenous circ-Foxo3 promoted cell proliferation. Ectopic expression of circ-Foxo3 repressed cell cycle progression by binding to the cell cycle proteins cyclin-dependent kinase 2 (also known as cell division protein kinase 2 or CDK2) and cyclin-dependent kinase inhibitor 1 (or p21), resulting in the formation of a ternary complex. 	loss of function, gain of function	NIH3T3, B16			p21 and CDK2	circRNA-protein	NIH3T3	RIP, RNA pull-down	The experiment showed that circ-Foxo3 was pulled-down by immunoprecipitation experiments with antibodies against CDK2 and p21, which did not pull-down linear Foxo3 mRNA. p21 and CDK2 were pulleddown by the probe but not by the control oligo in the circ-Foxo3-transfected cells.		
circ-Foxo3	circRNA	mus musculus	Foxo3						26873092	Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses.	Du WW, Yang W, Chen Y, Wu ZK, Foster FS, Yang Z, Li X, Yang BB.	Eur Heart J.  2017	highly expressed in heart samples of aged patients and mice	northern blots, RT-PCR, qRT-PCR, FISH	MEF, primary cardiomyocytes	ID-1, E2F1, FAK, and HIF1汐 interact with circ-Foxo3 and are retained in the cytoplasm and could no longer exert their anti-senescent and anti-stress roles, resulting in increased cellular senescence.	loss of function, gain of function	MEF, primary cardiomyocytes	6每8 weeks, BALB/c strain		ID1, E2F1, HIF1a, and FAK	circRNA-protein	MEF, primary cardiomyocytes	RIP, RNA pull-down	circ-Foxo3 was pulled down by antibodies against ID1, E2F1, FAK, and HIF1a, but the linear Foxo3 mRNA was not. It was found that circ-Foxo3 could pull down Id1, E2F1, HIF1a, and FAK from cells transfected with circ-Foxo3.		
MFACR	circRNA	mus musculus			mm9-circ-016597			cardiovascular diseases	28498369	Circular RNA mediates cardiomyocyte death via miRNA-dependent upregulation of MTP18 expression.	Wang K, Gan TY, Li N, Liu CY, Zhou LY, Gao JN, Chen C, Yan KW, Ponnusamy M, Zhang YH, Li PF.	Cell Death Differ.  2017	MFACR was expressed in the mouse heart.	qRT-PCR	mouse cardiomyocyte	MFACR regulates mitochondrial fission and apoptosis in the heart by directly targeting and downregulating miR-652-3p; this in turn blocks mitochondrial fission and cardiomyocyte cell death by suppressing MTP18 translation. MFACR directly sequesters miR-652-3p in the cytoplasm and inhibits its activity. MFACR knockdown in cardiomyocytes and mice attenuates mitochondrial fission and MI.	loss of function, gain of function	mouse cardiomyocyte	mouse I/R injury model of MI		miR-652-3p	circRNA-miRNA	mouse cardiomyocytes	RNA pull-down	these data indicate that MFACR can directly bind to miR-652-3p in vivo.	MTP18	
circRNA_000203	circRNA	mus musculus	Myo9a					diabetic cardiomyopathy	28079129	CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts.	Tang CM, Zhang M, Huang L, Hu ZQ, Zhu JN, Xiao Z, Zhang Z, Lin QX, Zheng XL, -Yang M, Wu SL, Cheng JD, Shan ZX.	Sci Rep.  2017	CircRNA_000203 was shown upregulated in the diabetic mouse myocardium and in Ang-II-induced mouse cardiac fibroblasts.	qRT-PCR	diabetic mouse myocardium	Enforced-expression of circRNA_000203 could increase expressions of Col1a2, Col3a1 and 汐-SMA in mouse cardiac fibroblasts. over-expression of circRNA_000203 could eliminate the anti-fibrosis effect of miR-26b-5p in cardiac fibroblasts.	gain of function	mouse cardiac fibroblasts			miR-26b-5p	circRNA-miRNA	HEK293 cells	RNA pull-down, qRT-PCR	RNA pull-down and RT-qPCR assay indicated that circRNA_000203 could specifically sponge miR-26b-5p.	Col1a2 and CTGF	
chr10:5403841-5426275-	circRNA	mus musculus			mm9_circ_001767			traumatic brain injury	29409384	Circular RNA expression alteration in exosomes from the brain extracellular space after traumatic brain injury in mice.	Zhao R, Zhou J, Dong X, Bi C, Jiang R, Dong J, Tian Y, Yuan H, Zhang JN.	J Neurotrauma.  2018	Significantly up-regulated in TBI group compared to Sham group.	RNA-seq, qRT-PCR	TBI group, Sham group												
chr5:115655901-115663886-	circRNA	mus musculus	Ccdc64					traumatic brain injury	29409384	Circular RNA expression alteration in exosomes from the brain extracellular space after traumatic brain injury in mice.	Zhao R, Zhou J, Dong X, Bi C, Jiang R, Dong J, Tian Y, Yuan H, Zhang JN.	J Neurotrauma.  2018	Significantly down-regulated in TBI group compared to Sham group.	RNA-seq, qRT-PCR	TBI group, Sham group												
chrX: 143709648-143744001-	circRNA	mus musculus						traumatic brain injury	29409384	Circular RNA expression alteration in exosomes from the brain extracellular space after traumatic brain injury in mice.	Zhao R, Zhou J, Dong X, Bi C, Jiang R, Dong J, Tian Y, Yuan H, Zhang JN.	J Neurotrauma.  2018	Significantly down-regulated in TBI group compared to Sham group.	RNA-seq, qRT-PCR	TBI group, Sham group												
chr12: 116871936-116901047-	circRNA	mus musculus	Ptprn2					traumatic brain injury	29409384	Circular RNA expression alteration in exosomes from the brain extracellular space after traumatic brain injury in mice.	Zhao R, Zhou J, Dong X, Bi C, Jiang R, Dong J, Tian Y, Yuan H, Zhang JN.	J Neurotrauma.  2018	Significantly up-regulated in TBI group compared to Sham group.	RNA-seq, qRT-PCR	TBI group, Sham group												
circ-Stk35	circRNA	mus musculus	Stk35		mm9_circ_002813			aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Increased expression between 22 mo versus 1 mo cortex samples was confirmed.	RNA-seq, qRT-PCR	22 mo cortex, 1 mo cortex												
circ-Zfp609	circRNA	mus musculus	Zfp609		mm9_circ_004501			aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Increased expression between 22 mo versus 1 mo cortex samples was confirmed.	RNA-seq, qRT-PCR	22 mo cortex, 1 mo cortex												
circ-Samd4	circRNA	mus musculus	Samd4		mm9_circ_005305			aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	RT-qPCR indicated a significant ~2-fold upregulation of circ-Samd4 in the aged cortex sample	RNA-seq, qRT-PCR	22 mo cortex, 1 mo cortex												
CDR1as	circRNA	mus musculus	Cdr1					aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Increased expression between 22 mo versus 1 mo cortex samples was confirmed.	RNA-seq, qRT-PCR	22 mo cortex, 1 mo cortex												
circ-Trpc6	circRNA	mus musculus	Trpc6		mm9_circ_013636			aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Increased expression between 22 mo versus 1 mo cortex samples was confirmed. significantly increased between 1 mo and 6 mo hippocampus. significantly increased between 6 mo and 22 mo hippocampus. 	RNA-seq, qRT-PCR	22 mo cortex, 1 mo cortex, 22 mo hippocampus, 6 mo hippocampus, 1 mo hippocampus.												
circ-INT	circRNA	mus musculus	INT		mm9_circ_017175			aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	Increased expression between 22 mo versus 1 mo cortex samples was confirmed. significantly increased between 1 mo and 6 mo hippocampus. significantly increased between 6 mo and 22 mo hippocampus. 	RNA-seq, qRT-PCR	22 mo cortex, 1 mo cortex, 22 mo hippocampus, 6 mo hippocampus, 1 mo hippocampus.												
circ-Ankib1	circRNA	mus musculus	Ankib1		mm9_circ_000903			aging	27958329	CircRNA accumulation in the aging mouse brain.	Gruner H, Cort矇s-L籀pez M, Cooper DA, Bauer M, Miura P.	Sci Rep.  2016	increased in 22 mo vs 1 mo cortex samples. Significantly increased at 6 mo compared to 1 mo. significantly increased between 6 mo and 22 mo hippocampus. 	RNA-seq, qRT-PCR	22 mo cortex, 6 mo cortex, 1 mo cortex, 22 mo hippocampus, 6 mo hippocampus, 1 mo hippocampus.												
m001237	circRNA	mus musculus	Ogdh						27476877	Characterization of circular RNAs in human, mouse and rat hearts.	Werfel S, Nothjunge S, Schwarzmayr T, Strom TM, Meitinger T, Engelhardt S.	J Mol Cell Cardiol.  2016	To further confirm the circularity of select candidates we quantified their enrichment in RNase R treated vs. mock treated samples using qPCR. We observed that circRNAs with higher predicted lengths showed lower enrichment, possibly due to minimal endonuclease contamination or small degree of RNA degradation during or after RNA isolation (m004295: 1.8 kb, m005505: 6.2 kb, m005504: 6,5 kb vs. m001237: 0.4 kb, m003757: 0.6 kb).	qRT-PCR	adult mouse heart												
m003757	circRNA	mus musculus	Lrch3						27476877	Characterization of circular RNAs in human, mouse and rat hearts.	Werfel S, Nothjunge S, Schwarzmayr T, Strom TM, Meitinger T, Engelhardt S.	J Mol Cell Cardiol.  2016	To further confirm the circularity of select candidates we quantified their enrichment in RNase R treated vs. mock treated samples using qPCR. We observed that circRNAs with higher predicted lengths showed lower enrichment, possibly due to minimal endonuclease contamination or small degree of RNA degradation during or after RNA isolation (m004295: 1.8 kb, m005505: 6.2 kb, m005504: 6,5 kb vs. m001237: 0.4 kb, m003757: 0.6 kb).	qRT-PCR	adult mouse heart												
m004295	circRNA	mus musculus	Slc8a1						27476877	Characterization of circular RNAs in human, mouse and rat hearts.	Werfel S, Nothjunge S, Schwarzmayr T, Strom TM, Meitinger T, Engelhardt S.	J Mol Cell Cardiol.  2016	To further confirm the circularity of select candidates we quantified their enrichment in RNase R treated vs. mock treated samples using qPCR. We observed that circRNAs with higher predicted lengths showed lower enrichment, possibly due to minimal endonuclease contamination or small degree of RNA degradation during or after RNA isolation (m004295: 1.8 kb, m005505: 6.2 kb, m005504: 6,5 kb vs. m001237: 0.4 kb, m003757: 0.6 kb).	qRT-PCR	adult mouse heart												
m005504	circRNA	mus musculus	Ttn						27476877	Characterization of circular RNAs in human, mouse and rat hearts.	Werfel S, Nothjunge S, Schwarzmayr T, Strom TM, Meitinger T, Engelhardt S.	J Mol Cell Cardiol.  2016	To further confirm the circularity of select candidates we quantified their enrichment in RNase R treated vs. mock treated samples using qPCR. We observed that circRNAs with higher predicted lengths showed lower enrichment, possibly due to minimal endonuclease contamination or small degree of RNA degradation during or after RNA isolation (m004295: 1.8 kb, m005505: 6.2 kb, m005504: 6,5 kb vs. m001237: 0.4 kb, m003757: 0.6 kb).	qRT-PCR	adult mouse heart												
m005505	circRNA	mus musculus	Ttn						27476877	Characterization of circular RNAs in human, mouse and rat hearts.	Werfel S, Nothjunge S, Schwarzmayr T, Strom TM, Meitinger T, Engelhardt S.	J Mol Cell Cardiol.  2016	To further confirm the circularity of select candidates we quantified their enrichment in RNase R treated vs. mock treated samples using qPCR. We observed that circRNAs with higher predicted lengths showed lower enrichment, possibly due to minimal endonuclease contamination or small degree of RNA degradation during or after RNA isolation (m004295: 1.8 kb, m005505: 6.2 kb, m005504: 6,5 kb vs. m001237: 0.4 kb, m003757: 0.6 kb).	qRT-PCR	adult mouse heart												
circRNA.19236	circRNA	mus musculus						osteoblast differentiation	28395271	Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells.	Qian DY, Yan GB, Bai B, Chen Y, Zhang SJ, Yao YC, Xia H.	Biomed Pharmacother.  2017	Increased in the BMP2-treated MC3T3-E1 cells.	RNA-seq, qRT-PCR	BMP2-treated MC3T3-E1 cells, control MC3T3-E1 cells												
circRNA.10042	circRNA	mus musculus						osteoblast differentiation	28395271	Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells.	Qian DY, Yan GB, Bai B, Chen Y, Zhang SJ, Yao YC, Xia H.	Biomed Pharmacother.  2017	Significantly increased in the BMP2-treated MC3T3-E1 cells.	RNA-seq, qRT-PCR	BMP2-treated MC3T3-E1 cells, control MC3T3-E1 cells												
circRNA.19142	circRNA	mus musculus						osteoblast differentiation	28395271	Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells.	Qian DY, Yan GB, Bai B, Chen Y, Zhang SJ, Yao YC, Xia H.	Biomed Pharmacother.  2017	Significantly increased in the BMP2-treated MC3T3-E1 cells.	RNA-seq, qRT-PCR	BMP2-treated MC3T3-E1 cells, control MC3T3-E1 cells												
circRNA.5846	circRNA	mus musculus						osteoblast differentiation	28395271	Differential circRNA expression profiles during the BMP2-induced osteogenic differentiation of MC3T3-E1 cells.	Qian DY, Yan GB, Bai B, Chen Y, Zhang SJ, Yao YC, Xia H.	Biomed Pharmacother.  2017	Significantly increased in the BMP2-treated MC3T3-E1 cells.	RNA-seq, qRT-PCR	BMP2-treated MC3T3-E1 cells, control MC3T3-E1 cells												
ciHnrnpu	circRNA	mus musculus	Hnrnpu					psychiatric disease	27113499	A Comprehensive Analysis of Cell Type-Specific Nuclear RNA From Neurons and Glia of the Brain.	Reddy AS, OBrien D, Pisat N, Weichselbaum CT, Sakers K, Lisci M, Dalal JS, Dougherty JD.	Biol Psychiatry.  2017	enriched in nuclei relative to cytoplasm and is found throughout the brain.	qRT-PCR	Cortex, Cerebellum, Forebrain/Midbrain, Hindbrain of mouse												
mmu_circRNA_003540	circRNA	mus musculus						Alzheimer＊s disease	29448241	Comprehensive analysis of differentially expressed profiles of Alzheimers disease associated circular RNAs in an Alzheimers disease mouse model.	Huang JL, Qin MC, Zhou Y, Xu ZH, Yang SM, Zhang F, Zhong J, Liang MK, Chen B, Zhang WY, Wu DP, Zhong ZG.	Aging (Albany NY).  2018	Significantly differed between the hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1 (P<0.05)	microarray, qRT-PCR	hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1												
mmu_circRNA_006173	circRNA	mus musculus						Alzheimer＊s disease	29448241	Comprehensive analysis of differentially expressed profiles of Alzheimers disease associated circular RNAs in an Alzheimers disease mouse model.	Huang JL, Qin MC, Zhou Y, Xu ZH, Yang SM, Zhang F, Zhong J, Liang MK, Chen B, Zhang WY, Wu DP, Zhong ZG.	Aging (Albany NY).  2018	Significantly differed between the hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1 (P<0.05)	microarray, qRT-PCR	hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1												
mmu_circRNA_012180	circRNA	mus musculus						Alzheimer＊s disease	29448241	Comprehensive analysis of differentially expressed profiles of Alzheimers disease associated circular RNAs in an Alzheimers disease mouse model.	Huang JL, Qin MC, Zhou Y, Xu ZH, Yang SM, Zhang F, Zhong J, Liang MK, Chen B, Zhang WY, Wu DP, Zhong ZG.	Aging (Albany NY).  2018	Significantly differed between the hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1 (P<0.05)	microarray, qRT-PCR	hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1												
mmu_circRNA_013699	circRNA	mus musculus						Alzheimer＊s disease	29448241	Comprehensive analysis of differentially expressed profiles of Alzheimers disease associated circular RNAs in an Alzheimers disease mouse model.	Huang JL, Qin MC, Zhou Y, Xu ZH, Yang SM, Zhang F, Zhong J, Liang MK, Chen B, Zhang WY, Wu DP, Zhong ZG.	Aging (Albany NY).  2018	Significantly differed between the hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1 (P<0.05)	microarray, qRT-PCR	hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1												
mmu_circRNA_017963	circRNA	mus musculus						Alzheimer＊s disease	29448241	Comprehensive analysis of differentially expressed profiles of Alzheimers disease associated circular RNAs in an Alzheimers disease mouse model.	Huang JL, Qin MC, Zhou Y, Xu ZH, Yang SM, Zhang F, Zhong J, Liang MK, Chen B, Zhang WY, Wu DP, Zhong ZG.	Aging (Albany NY).  2018	Significantly differed between the hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1 (P<0.05)	microarray, qRT-PCR	hippocampal tissues of 10-month-old SAMP8 and age-matched SAMR1												
chr11:29705535|29708770	circRNA	mus musculus	Rtn4						29253603	Region-specific expression of circular RNAs in the mouse brain.	Chen BJ, Yang B, Janitz M.	Neurosci Lett.  2018	Experimental validation, using RT-qPCR and independent RNA sample set, of the differentially expressed circRNA between hippocampus and frontal cortex, corroborated outcomes of the RNA-Seq data analysis	RNA-seq, qRT-PCR	hippocampus (HC) and prefrontal cortex (PFC) of mouse brain												
chr3:122781567|122818067	circRNA	mus musculus	Pde5a						29253603	Region-specific expression of circular RNAs in the mouse brain.	Chen BJ, Yang B, Janitz M.	Neurosci Lett.  2018	Experimental validation, using RT-qPCR and independent RNA sample set, of the differentially expressed circRNA between hippocampus and frontal cortex, corroborated outcomes of the RNA-Seq data analysis	RNA-seq, qRT-PCR	hippocampus (HC) and prefrontal cortex (PFC) of mouse brain												
chr4:13835633|13846957	circRNA	mus musculus	Runx1t1						29253603	Region-specific expression of circular RNAs in the mouse brain.	Chen BJ, Yang B, Janitz M.	Neurosci Lett.  2018	Experimental validation, using RT-qPCR and independent RNA sample set, of the differentially expressed circRNA between hippocampus and frontal cortex, corroborated outcomes of the RNA-Seq data analysis	RNA-seq, qRT-PCR	hippocampus (HC) and prefrontal cortex (PFC) of mouse brain												
circ-Ttn	circRNA	mus musculus	Ttn					Doxorubicin-Mediated Cardiotoxicity	29133306	Quaking Inhibits Doxorubicin-Mediated Cardiotoxicity Through Regulation of Cardiac Circular RNA Expression.	Gupta SK, Garg A, B瓣r C, Chatterjee S, Foinquinos A, Milting H, Streckfu壟-Bomeke K, Fiedler J, Thum T.	Circ Res.  2018	Significantly changed in pLV (plasmid Lentivirus) empty, pLV Qki5, CRi empty, CRi 3+4 Qki, and CRi 5+6 Qki HL-1 cell lines. Positively regulated with Qki expression. Downregulated with doxorubicin treatment in HL-1 cells. Downregulated in mouse hearts, which had doxorubicin-induced reductions in Qki levels. Downregulated in control (pLV empty) cells exposed to doxorubicin compared with pLV Qki5-overexpressing cells.	qRT-PCR	HL-1 cell lines	we inhibited Ttn 105每111 circular RNA by a specific siRNA approach (Figure 3G) and evaluated its effect on doxorubicin-induced apoptosis. SiRNA mediated inhibition of Ttn 105每111 led to increased susceptibility to doxorubicin as evident by higher caspase activity. Additionally, the knockdown of Ttn 105每111 in pLV Qki5-overexpressing cell line also resulted in an induced caspase activity. On the contrary, lentiviral mediated overexpression of circular RNA Ttn 105每111 resulted in lower caspase 3/7 activity and increased survival as seen by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay (Online Figure IVD though IVF).	loss of function, gain of function	HL-1 cell lines									
circArhgap32	circRNA	mus musculus	Arhgap32					Doxorubicin-Mediated Cardiotoxicity	29133306	Quaking Inhibits Doxorubicin-Mediated Cardiotoxicity Through Regulation of Cardiac Circular RNA Expression.	Gupta SK, Garg A, B瓣r C, Chatterjee S, Foinquinos A, Milting H, Streckfub-Bomeke K, Fiedler J, Thum T.	Circ Res.  2018	Significantly changed in pLV (plasmid Lentivirus) empty, pLV Qki5, CRi empty, CRi 3+4 Qki, and CRi 5+6 Qki HL-1 cell lines. Negtively regulated with Qki expression. Downregulated with doxorubicin treatment in HL-1 cells.	qRT-PCR	HL-1 cell lines												
circ-Strn3	circRNA	mus musculus	Strn3					Doxorubicin-Mediated Cardiotoxicity	29133306	Quaking Inhibits Doxorubicin-Mediated Cardiotoxicity Through Regulation of Cardiac Circular RNA Expression.	Gupta SK, Garg A, B瓣r C, Chatterjee S, Foinquinos A, Milting H, Streckfu壟-Bomeke K, Fiedler J, Thum T.	Circ Res.  2018	Significantly changed in pLV (plasmid Lentivirus) empty, pLV Qki5, CRi empty, CRi 3+4 Qki, and CRi 5+6 Qki HL-1 cell lines. Positively regulated with Qki expression. Downregulated with doxorubicin treatment in HL-1 cells. Downregulated in mouse hearts, which had doxorubicin-induced reductions in Qki levels. Downregulated in control (pLV empty) cells exposed to doxorubicin compared with pLV Qki5-overexpressing cells.	qRT-PCR	HL-1 cell lines												
circ-Fhod3	circRNA	mus musculus	Fhod3					Doxorubicin-Mediated Cardiotoxicity	29133306	Quaking Inhibits Doxorubicin-Mediated Cardiotoxicity Through Regulation of Cardiac Circular RNA Expression.	Gupta SK, Garg A, B瓣r C, Chatterjee S, Foinquinos A, Milting H, Streckfu壟-Bomeke K, Fiedler J, Thum T.	Circ Res.  2018	Significantly changed in pLV (plasmid Lentivirus) empty, pLV Qki5, CRi empty, CRi 3+4 Qki, and CRi 5+6 Qki HL-1 cell lines. Positively regulated with Qki expression. Downregulated with doxorubicin treatment in HL-1 cells. Downregulated in mouse hearts, which had doxorubicin-induced reductions in Qki levels. Downregulated in control (pLV empty) cells exposed to doxorubicin compared with pLV Qki5-overexpressing cells. 	qRT-PCR	HL-1 cell lines												
mmu-circRNA-015947	circRNA	mus musculus							26845359	Circular RNA expression alterations are involved in OGD/R-induced neuron injury.	Lin SP, Ye S, Long Y, Fan Y, Mao HF, Chen MT, Ma QJ.	Biochem Biophys Res Commun.  2016	up-regulated in the OGD/R group	microarray, qRT-PCR	HT22, OGD/R HT22 cells												
circRNA.2483	circRNA	mus musculus						Osteoarthritis	29247798	Circular RNA expression profile of articular chondrocytes in an IL-1帣-induced mouse model of osteoarthritis.	Zhou Z, Du D, Chen A, Zhu L.	Gene.  2018	Down-regulated in IL-1汕-induced mouse articular chondrocytes compared to controls.	RNA-seq, qRT-PCR	IL-1汕-induced mouse articular chondrocytes, controls												
circRNA.33736	circRNA	mus musculus						Osteoarthritis	29247798	Circular RNA expression profile of articular chondrocytes in an IL-1帣-induced mouse model of osteoarthritis.	Zhou Z, Du D, Chen A, Zhu L.	Gene.  2018	Down-regulated in IL-1汕-induced mouse articular chondrocytes compared to controls.	RNA-seq, qRT-PCR	IL-1汕-induced mouse articular chondrocytes, controls												
circRNA.2443	circRNA	mus musculus						Osteoarthritis	29247798	Circular RNA expression profile of articular chondrocytes in an IL-1帣-induced mouse model of osteoarthritis.	Zhou Z, Du D, Chen A, Zhu L.	Gene.  2018	Up-regulated in IL-1汕-induced mouse articular chondrocytes compared to controls.	RNA-seq, qRT-PCR	IL-1汕-induced mouse articular chondrocytes, controls												
circRNA.33186	circRNA	mus musculus						Osteoarthritis	29247798	Circular RNA expression profile of articular chondrocytes in an IL-1帣-induced mouse model of osteoarthritis.	Zhou Z, Du D, Chen A, Zhu L.	Gene.  2018	Up-regulated in IL-1汕-induced mouse articular chondrocytes compared to controls.	RNA-seq, qRT-PCR	IL-1汕-induced mouse articular chondrocytes, controls												
circRNA.7063	circRNA	mus musculus						Osteoarthritis	29247798	Circular RNA expression profile of articular chondrocytes in an IL-1帣-induced mouse model of osteoarthritis.	Zhou Z, Du D, Chen A, Zhu L.	Gene.  2018	Up-regulated in IL-1汕-induced mouse articular chondrocytes compared to controls.	RNA-seq, qRT-PCR	IL-1汕-induced mouse articular chondrocytes, controls												
c-13	circRNA	mus musculus			circ_0273			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-75	circRNA	mus musculus			circ_0907			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-76	circRNA	mus musculus			circ_0919			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-77	circRNA	mus musculus			circ_0920			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-27	circRNA	mus musculus			circ_1165			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-02	circRNA	mus musculus			circ_1223			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-88	circRNA	mus musculus			circ_1224			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-48	circRNA	mus musculus			circ_1733			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-78	circRNA	mus musculus			circ_2111			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-79	circRNA	mus musculus			circ_2193			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-84	circRNA	mus musculus			circ_2254			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-82	circRNA	mus musculus			circ_3217			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-01	circRNA	mus musculus			circ_3279			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-83	circRNA	mus musculus			circ_3834			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-80	circRNA	mus musculus			circ_4484			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-87	circRNA	mus musculus			circ_5306			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-45	circRNA	mus musculus			circ_5313			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-52	circRNA	mus musculus			circ_5622			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-31	circRNA	mus musculus			circ_5722			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-03	circRNA	mus musculus			circ_5846			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
c-16	circRNA	mus musculus			circ_5906			amyotrophic lateral sclerosis	28358055	FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons.	Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarf簷 R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I.	Nat Commun.  2017	The expression of the circRNA was then measured by quantitative RT每PCR in GFP+-FUS+/+ and GFP+-FUS-/- MNs and all of them resulted significantly deregulated, in agreement with RNA-seq in FUS-/- conditions.	RNA-seq, qRT-PCR	in vitro-derived mouse motor neurons												
circ_001729	circRNA	mus musculus						Transient Focal Ischemia	28701578	Circular RNA Expression Profiles Alter Significantly in Mouse Brain After Transient Focal Ischemia.	Mehta SL, Pandi G, Vemuganti R.	Stroke.  2017	The circRNAs circ_001729 was observed to be downregulated significantly at 6 hours reperfusion after transient MCAO compared with sham similar to the microarray data.	microarray, qRT-PCR	male C57BL/6J mice brain												
circ_006696	circRNA	mus musculus						Transient Focal Ischemia	28701578	Circular RNA Expression Profiles Alter Significantly in Mouse Brain After Transient Focal Ischemia.	Mehta SL, Pandi G, Vemuganti R.	Stroke.  2017	The circRNAs circ_006696 was observed to be downregulated significantly at 6 hours reperfusion after transient MCAO compared with sham similar to the microarray data.	microarray, qRT-PCR	male C57BL/6J mice brain												
circ_008018	circRNA	mus musculus						Transient Focal Ischemia	28701578	Circular RNA Expression Profiles Alter Significantly in Mouse Brain After Transient Focal Ischemia.	Mehta SL, Pandi G, Vemuganti R.	Stroke.  2017	The circRNAs circ_008018 was observed to be upregulated significantly at 6 hours reperfusion after transient MCAO compared with sham similar to the microarray data.	microarray, qRT-PCR	male C57BL/6J mice brain												
circ_011137	circRNA	mus musculus						Transient Focal Ischemia	28701578	Circular RNA Expression Profiles Alter Significantly in Mouse Brain After Transient Focal Ischemia.	Mehta SL, Pandi G, Vemuganti R.	Stroke.  2017	The circRNAs circ_011137 was observed to be downregulated significantly at 6 hours reperfusion after transient MCAO compared with sham similar to the microarray data.	microarray, qRT-PCR	male C57BL/6J mice brain												
circ_015350	circRNA	mus musculus						Transient Focal Ischemia	28701578	Circular RNA Expression Profiles Alter Significantly in Mouse Brain After Transient Focal Ischemia.	Mehta SL, Pandi G, Vemuganti R.	Stroke.  2017	The circRNAs circ_015350 was observed to be upregulated significantly at 6 hours reperfusion after transient MCAO compared with sham similar to the microarray data.	microarray, qRT-PCR	male C57BL/6J mice brain												
circ_016128	circRNA	mus musculus						Transient Focal Ischemia	28701578	Circular RNA Expression Profiles Alter Significantly in Mouse Brain After Transient Focal Ischemia.	Mehta SL, Pandi G, Vemuganti R.	Stroke.  2017	The circRNAs circ_016128 was observed to be upregulated significantly at 6 hours reperfusion after transient MCAO compared with sham similar to the microarray data.	microarray, qRT-PCR	male C57BL/6J mice brain												
circ-Foxo3	circRNA	mus musculus	Foxo3						27713910	The anti-cancer components of Ganoderma lucidum possesses cardiovascular protective effect by regulating circular RNA expression.	Xie YZ, Yang F, Tan W, Li X, Jiao C, Huang R, Yang BB.	Oncoscience.  2016	Treatment with Ganoderma spore oil decreases expression of circ-Foxo3	qRT-PCR	mice orally delivered with Ganoderma spore oil (GSO), Mouse cardiac fibroblasts treated with different concentrations of GSO												
cdr1AS 	circRNA	mus musculus	Cdr1						23446348	Circular RNAs are a large class of animal RNAs with regulatory potency.	Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, Loewer A, Ziebold U, Landthaler M, Kocks C, le Noble F, Rajewsky N.	Nature.  2013	The circRNA was validated experimentally.	qRT-PCR, sanger sequencing	mouse adult brain												
mus-circAFF1	circRNA	mus musculus	AFF1						23446348	Circular RNAs are a large class of animal RNAs with regulatory potency.	Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, Loewer A, Ziebold U, Landthaler M, Kocks C, le Noble F, Rajewsky N.	Nature.  2013	The circRNA was validated experimentally.	qRT-PCR, sanger sequencing	mouse adult brain												
mus-circHIPK3	circRNA	mus musculus	HIPK3						23446348	Circular RNAs are a large class of animal RNAs with regulatory potency.	Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, Loewer A, Ziebold U, Landthaler M, Kocks C, le Noble F, Rajewsky N.	Nature.  2013	The circRNA was validated experimentally.	qRT-PCR, sanger sequencing	mouse adult brain												
mus-circLRP6	circRNA	mus musculus	LRP6						23446348	Circular RNAs are a large class of animal RNAs with regulatory potency.	Memczak S, Jens M, Elefsinioti A, Torti F, Krueger J, Rybak A, Maier L, Mackowiak SD, Gregersen LH, Munschauer M, Loewer A, Ziebold U, Landthaler M, Kocks C, le Noble F, Rajewsky N.	Nature.  2013	The circRNA was validated experimentally.	qRT-PCR, sanger sequencing	mouse adult brain												
circFmn	circRNA	mus musculus	Fmn						9848078	The mouse formin (Fmn) gene: abundant circular RNA transcripts and gene-targeted deletion analysis.	Chao CW, Chan DC, Kuo A, Leder P.	Mol Med.  1998	RT-PCR and ribonuclease protection analyses indicate that these transcripts are circular and are the major transcripts arising from this locus in adult brain and kidney.	RT-PCR	mouse adult brain and kidney												
circRIMS1	circRNA	mus musculus	RIMS1						27543790	Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes.	Xia S, Feng J, Lei L, Hu J, Xia L, Wang J, Xiang Y, Liu L, Zhong S, Han L, He C.	Brief Bioinform.  2017	To validate the existence of TS circRNA, we perform RT-PCR experiment based on mouse tissues. TS circRNAs from five mouse tissues including the brain, heart, liver, lung and thymus were validated. These TS circRNAs are generated from exons of five protein-coding genes: RIMS1 in brain, PDE4DIP in heart, ADK in liver, LAMP3 in lung and SATB1 in thymus separately.	qRT-PCR	mouse brain												
circRNA Trerf1	circRNA	mus musculus	Trerf1					lead induced neuronal cell apoptosis	27604105	A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis.	Nan A, Chen L, Zhang N, Liu Z, Yang T, Wang Z, Yang C, Jiang Y.	Arch Toxicol.  2017	circRNA Trerf1 level showed no change upon injury.	qRT-PCR	mouse cerebellum, pons, medulla oblongata, hippocampus and cerebral cortex. lead-treated N2a mouse nerve cells												
circPDE4DIP	circRNA	mus musculus	PDE4DIP						27543790	Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes.	Xia S, Feng J, Lei L, Hu J, Xia L, Wang J, Xiang Y, Liu L, Zhong S, Han L, He C.	Brief Bioinform.  2017	To validate the existence of TS circRNA, we perform RT-PCR experiment based on mouse tissues. TS circRNAs from five mouse tissues including the brain, heart, liver, lung and thymus were validated. These TS circRNAs are generated from exons of five protein-coding genes: RIMS1 in brain, PDE4DIP in heart, ADK in liver, LAMP3 in lung and SATB1 in thymus separately.	qRT-PCR	mouse heart												
circHipk3-1	circRNA	mus musculus	HIPK3						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circMyh6-4	circRNA	mus musculus	Myh6						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circMyocd-3	circRNA	mus musculus	Myocd						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circNfix-3	circRNA	mus musculus	Nfix						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circRyr2-3	circRNA	mus musculus	Ryr2						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circSlc8a1-1	circRNA	mus musculus	Slc8a1						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circTank-1	circRNA	mus musculus	Tank						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circTcf20-2	circRNA	mus musculus	Tcf20						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circTpm1-3	circRNA	mus musculus	Tpm1						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circTrak1-2	circRNA	mus musculus	Trak1						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circTtn-32	circRNA	mus musculus	Ttn						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circTtn-63	circRNA	mus musculus	Ttn						28082450	A landscape of circular RNA expression in the human heart.	Tan WL, Lim BT, Anene-Nzelu CG, Ackers-Johnson M, Dashi A, See K, Tiang Z, Lee DP, Chua WW, Luu TD, Li PY, Richards AM, Foo RS.	Cardiovasc Res.  2017	we definitively confirmed the back-spliced structure of 24/30 and 19/20 of human and mouse cardiac circRNA candidates by RT-PCR using junction-specific divergent primers and Sanger sequencing.	qRT-PCR	mouse hearts												
circADK	circRNA	mus musculus	ADK						27543790	Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes.	Xia S, Feng J, Lei L, Hu J, Xia L, Wang J, Xiang Y, Liu L, Zhong S, Han L, He C.	Brief Bioinform.  2017	To validate the existence of TS circRNA, we perform RT-PCR experiment based on mouse tissues. TS circRNAs from five mouse tissues including the brain, heart, liver, lung and thymus were validated. These TS circRNAs are generated from exons of five protein-coding genes: RIMS1 in brain, PDE4DIP in heart, ADK in liver, LAMP3 in lung and SATB1 in thymus separately.	qRT-PCR	mouse liver												
circLAMP3	circRNA	mus musculus	LAMP3						27543790	Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes.	Xia S, Feng J, Lei L, Hu J, Xia L, Wang J, Xiang Y, Liu L, Zhong S, Han L, He C.	Brief Bioinform.  2017	To validate the existence of TS circRNA, we perform RT-PCR experiment based on mouse tissues. TS circRNAs from five mouse tissues including the brain, heart, liver, lung and thymus were validated. These TS circRNAs are generated from exons of five protein-coding genes: RIMS1 in brain, PDE4DIP in heart, ADK in liver, LAMP3 in lung and SATB1 in thymus separately.	qRT-PCR	mouse lung												
Circ_Dcbld2	circRNA	mus musculus	Dcbld2					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Acvr2a	circRNA	mus musculus	Acvr2a					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Adamts6	circRNA	mus musculus	Adamts6					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Ankib1	circRNA	mus musculus	Ankib1					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Ash1l	circRNA	mus musculus	Ash1l					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Asph	circRNA	mus musculus	Asph					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Bach1	circRNA	mus musculus	Bach1					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Bnc2	circRNA	mus musculus	Bnc2					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Camsap1	circRNA	mus musculus	Camsap1					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Cdyl	circRNA	mus musculus	Cdyl					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Crkl	circRNA	mus musculus	Crkl					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Hipk3	circRNA	mus musculus	HIPK3					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Med13l	circRNA	mus musculus	Med13l					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Mef2a	circRNA	mus musculus	Mef2a					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Myl4	circRNA	mus musculus	Myl4					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Neb	circRNA	mus musculus	Neb					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Pms1	circRNA	mus musculus	Pms1					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Ptp4a2	circRNA	mus musculus	Ptp4a2					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Qk	circRNA	mus musculus						Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Rtn4	circRNA	mus musculus	Rtn4					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-RTN4bis	circRNA	mus musculus						Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Runx1	circRNA	mus musculus	Runx1					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Sept9	circRNA	mus musculus	Sept9					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Slc8a1	circRNA	mus musculus	SLC8A1					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Specc1	circRNA	mus musculus	Specc1					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Tmeff1	circRNA	mus musculus	Tmeff1					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Ttn	circRNA	mus musculus	Ttn					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Zfhx3	circRNA	mus musculus	Zfhx3					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Zfp292	circRNA	mus musculus	Zfp292					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Circ-Zfp609	circRNA	mus musculus	Zfp609					Duchenne muscular dystrophy	28344082	Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis.	Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, Fatica A, Santini T, Andronache A, Wade M, Laneve P, Rajewsky N, Bozzoni I.	Mol Cell.  2017	The normalized RNA quantities measured by qRT-PCR reflected the levels observed by RNA-seq and RT-PCR.	RNA-seq, qRT-PCR	mouse myoblasts												
Sry circular RNA	circRNA	mus musculus	Sry						7684656	Circular transcripts of the testis-determining gene Sry in adult mouse testis.	Capel B, Swain A, Nicolis S, Hacker A, Walter M, Koopman P, Goodfellow P, Lovell-Badge R.	Cell.  1993	A non-translated circular Sry transcript is expressed in mouse	RT-PCR	mouse testis												
circSATB1	circRNA	mus musculus	SATB1						27543790	Comprehensive characterization of tissue-specific circular RNAs in the human and mouse genomes.	Xia S, Feng J, Lei L, Hu J, Xia L, Wang J, Xiang Y, Liu L, Zhong S, Han L, He C.	Brief Bioinform.  2017	To validate the existence of TS circRNA, we perform RT-PCR experiment based on mouse tissues. TS circRNAs from five mouse tissues including the brain, heart, liver, lung and thymus were validated. These TS circRNAs are generated from exons of five protein-coding genes: RIMS1 in brain, PDE4DIP in heart, ADK in liver, LAMP3 in lung and SATB1 in thymus separately.	qRT-PCR	mouse thymus												
circMyst4	circRNA	mus musculus	Myst4						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	increased over the course of development	RNA-seq, qRT-PCR	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circDscam	circRNA	mus musculus	Dscam						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	abundant particles present in the cell body and distributed particles observed throughout the dendritic arbor	RNA-seq, qRT-PCR, FISH	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circElavl3	circRNA	mus musculus	Elavl3						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	abundant particles present in the cell body and distributed particles observed throughout the dendritic arbor	RNA-seq, qRT-PCR, FISH	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circNbea	circRNA	mus musculus	Nbea						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	abundant particles present in the cell body and distributed particles observed throughout the dendritic arbor	RNA-seq, qRT-PCR, FISH	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circNlgn1	circRNA	mus musculus	Nlgn1						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	abundant particles present in the cell body and distributed particles observed throughout the dendritic arbor	RNA-seq, qRT-PCR, FISH	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circRmst	circRNA	mus musculus	Rmst						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	abundant particles present in the cell body and distributed particles observed throughout the dendritic arbor	RNA-seq, qRT-PCR, FISH	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circEzh2	circRNA	mus musculus	Ezh2						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	detected in brain tissues	RNA-seq, RT-PCR, qRT-PCR	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circUbe2k	circRNA	mus musculus	Ube2k						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	detected in brain tissues	RNA-seq, RT-PCR, qRT-PCR	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circUnc79	circRNA	mus musculus	Unc79						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	detected in brain tissues	RNA-seq, RT-PCR, qRT-PCR	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circAagab	circRNA	mus musculus	Aagab						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	increased over the course of development	RNA-seq, RT-PCR, qRT-PCR	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circC2cd5	circRNA	mus musculus	C2cd5						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	increased over the course of development	RNA-seq, RT-PCR, qRT-PCR	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circDigap1	circRNA	mus musculus	Digap1						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	increased over the course of development	RNA-seq, RT-PCR, qRT-PCR	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circDtnb	circRNA	mus musculus	Dtnb						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	increased over the course of development	RNA-seq, RT-PCR, qRT-PCR	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circGigyf2	circRNA	mus musculus	Gigyf2						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	abundant particles present in the cell body and distributed particles observed throughout the dendritic arbor	RNA-seq, RT-PCR, qRT-PCR, FISH	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circKlhl2	circRNA	mus musculus	Klhl2						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	exhibited strong upregulation during development	RNA-seq, RT-PCR, qRT-PCR, FISH	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												
circHomer1	circRNA	mus musculus	Homer1						25714049	Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity.	You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, Akbalik G, Wang M, Glock C, Quedenau C, Wang X, Hou J, Liu H, Sun W, Sambandan S, Chen T, Schuman EM, Chen W.	Nat Neurosci.  2015	significantly upregulated in primary hippocampal neurons (P < 0.0005 for somata and P < 0.0208 for dendrites) and hippocampal slices	RNA-seq, RT-PCR, qRT-PCR, FISH	mouse tissues, including brain, heart, liver, lung and testis, hippocampi of adult mice and rat												circRNA expression levels are regulated by neural plasticity
ciRS-7	circRNA	mus musculus	Cdr1		Cdr1as			myocardial infarction	26998750	The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression.	Geng HH, Li R, Su YM, Xiao J, Pan M, Cai XX, Ji XP.	PLoS One.  2016	Co-Expression of Cdr1as and miR-7a Was Detected during MI-Induced Injury or in Hypoxia-Treated Cardiomyocytes. upregulated in MI mice with increased cardiac infarct size, or cardiomyocytes under hypoxia treatment.	qRT-PCR	myocardial tissues from MI mice, primary cardiomyocytes, MCM (mouse cardiac myocytes) cells	Overexpression of Cdr1as Aggravated MI Injuries with Upregulated PARP and SP1, which Could Be Rescued by the Co-Overexpression of miR-7a. Cdr1as overexpression in MCM cells promoted cell apoptosis, but was then reversed by miR-7a overexpression.	gain of function	Primary cardiomyocytes, mouse cardiac myocytes, MCM cells	Male C57BL/6 mice of 8-week-old		miR-7a/b	circRNA-miRNA	MCM		well-identified circular RNAs (circRNAs), as a miR-7a/b sponge or inhibitor in brain tissues or islet cells	PARP, SP1	
circRNA_002581	circRNA	mus musculus						nonalcoholic steatohepatitis	27677588	CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis.	Jin X, Feng CY, Xiang Z, Chen YP, Li YM.	Oncotarget.  2016	differentially expressed between NASH and control groups.	qRT-PCR	NASH mice model and controls												
circRNA_007585	circRNA	mus musculus						nonalcoholic steatohepatitis	27677588	CircRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of nonalcoholic steatohepatitis.	Jin X, Feng CY, Xiang Z, Chen YP, Li YM.	Oncotarget.  2016	differentially expressed between NASH and control groups.	qRT-PCR	NASH mice model and controls												
circStk39	circRNA	mus musculus	Stk39						25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	circStk39 was validated experimentally.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circDym	circRNA	mus musculus	Dym						25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	We found several circRNAs enriched in specific brain regions〞independent of their linear isoforms. Some circRNAs were highly enriched in the cerebellum: circRims2, circElf2, and circDym, while circPlxnd1 was enriched in the cortex.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circPlxnd1	circRNA	mus musculus	Plxnd1						25921068	Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed.	Rybak-Wolf A, Stottmeister C, Gla鱉ar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N.	Mol Cell.  2015	We found several circRNAs enriched in specific brain regions〞independent of their linear isoforms. Some circRNAs were highly enriched in the cerebellum: circRims2, circElf2, and circDym, while circPlxnd1 was enriched in the cortex.	qRT-PCR, northern blots	P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5每E18.5)												
circFxr2	circRNA	mus musculus	Fxr2					pigmentation	29377327	Comprehensive circRNA expression profile and construction of circRNA-associated ceRNA network in fur skin.	Zhu Z, Li Y, Liu W, He J, Zhang L, Li H, Li P, Lv L.	Exp Dermatol.  2018	highly expressed in BE compared with WE (P > .01)	RNA-seq, qRT-PCR	postnatal black fur skin (BP), postnatal of white fur skin (WP), embryo of white fur skin (WE), embryo of black fur skin (BE)												
circAtrnl1	circRNA	mus musculus	Atrnl1					pigmentation	29377327	Comprehensive circRNA expression profile and construction of circRNA-associated ceRNA network in fur skin.	Zhu Z, Li Y, Liu W, He J, Zhang L, Li H, Li P, Lv L.	Exp Dermatol.  2018	highly expressed in BP compared with WP (P > .01), and highly expressed in BE compared WE.	RNA-seq, qRT-PCR	postnatal black fur skin (BP), postnatal of white fur skin (WP), embryo of white fur skin (WE), embryo of black fur skin (BE)												
circKansl1l	circRNA	mus musculus	Kansl1l					pigmentation	29377327	Comprehensive circRNA expression profile and construction of circRNA-associated ceRNA network in fur skin.	Zhu Z, Li Y, Liu W, He J, Zhang L, Li H, Li P, Lv L.	Exp Dermatol.  2018	highly expressed in BP compared with WP (P > .01), and highly expressed in BE compared WE.	RNA-seq, qRT-PCR	postnatal black fur skin (BP), postnatal of white fur skin (WP), embryo of white fur skin (WE), embryo of black fur skin (BE)												
circHdac4	circRNA	mus musculus	Hdac4					pigmentation	29377327	Comprehensive circRNA expression profile and construction of circRNA-associated ceRNA network in fur skin.	Zhu Z, Li Y, Liu W, He J, Zhang L, Li H, Li P, Lv L.	Exp Dermatol.  2018	highly expressed in BP compared with WP (P > .05)	RNA-seq, qRT-PCR	postnatal black fur skin (BP), postnatal of white fur skin (WP), embryo of white fur skin (WE), embryo of black fur skin (BE)												
mmu_circRNA_004507	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	down regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_006860	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	down regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_007653	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	down regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_009088	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	down regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_017693	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	down regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_003539	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	up regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_005444	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	up regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_007438	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	up regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_007873	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	up regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mmu_circRNA_008887	circRNA	mus musculus						osteoclastogenesis	26856880	Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis.	Dou C, Cao Z, Yang B, Ding N, Hou T, Luo F, Kang F, Li J, Yang X, Jiang H, Xiang J, Quan H, Xu J, Dong S.	Sci Rep.  2016	up regulated circRNAs among all comparison groups normalized to GAPDH.	qRT-PCR	RAW264.7 cells												
mcircRasGEF1B	circRNA	mus musculus							27362560	Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway.	Ng WL, Marinov GK, Liau ES, Lam YL, Lim YY, Ea CK.	RNA Biol.  2016	Expression of mcircRasGEF1B was robustly induced by LPS and ODN CpG DNA, and to a lesser extent by poly I:C and Pam3CSK4.	RNA-seq, qRT-PCR	RAW264.7 cells, MEF	mcircRasGEF1B regulates the expression of ICAM-1 in the LPS/TLR4 signaling pathway	loss of function	RAW264.7									
mcircEtv6	circRNA	mus musculus							27362560	Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway.	Ng WL, Marinov GK, Liau ES, Lam YL, Lim YY, Ea CK.	RNA Biol.  2016	expressed in mouse macrophage	RNA-seq, qRT-PCR	RAW264.7 cells, MEF												
mcircLilrb3	circRNA	mus musculus							27362560	Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway.	Ng WL, Marinov GK, Liau ES, Lam YL, Lim YY, Ea CK.	RNA Biol.  2016	expressed in mouse macrophage	RNA-seq, qRT-PCR	RAW264.7 cells, MEF												
mcircPlcl2	circRNA	mus musculus							27362560	Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway.	Ng WL, Marinov GK, Liau ES, Lam YL, Lim YY, Ea CK.	RNA Biol.  2016	expressed in mouse macrophage	RNA-seq, qRT-PCR	RAW264.7 cells, MEF												
mcircUbe2d2	circRNA	mus musculus							27362560	Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway.	Ng WL, Marinov GK, Liau ES, Lam YL, Lim YY, Ea CK.	RNA Biol.  2016	expressed in mouse macrophage	RNA-seq, qRT-PCR	RAW264.7 cells, MEF												
mm10_circ_0011857	circRNA	mus musculus						Alzheimer＊s disease	28669840	Characterization of circRNA-Associated-ceRNA Networks in a Senescence-Accelerated Mouse Prone 8 Brain.	Zhang S, Zhu D, Li H, Li H, Feng C, Zhang W.	Mol Ther.  2017	Down-regulated in SAMP8 brain compared to SAMP1.	RNA-seq, qRT-PCR	SAMP8 brain, SAMP1 brain												
mm10_circ_0007422	circRNA	mus musculus						Alzheimer＊s disease	28669840	Characterization of circRNA-Associated-ceRNA Networks in a Senescence-Accelerated Mouse Prone 8 Brain.	Zhang S, Zhu D, Li H, Li H, Feng C, Zhang W.	Mol Ther.  2017	Up-regulated in SAMP8 brain compared to SAMP1.	RNA-seq, qRT-PCR	SAMP8 brain, SAMP1 brain												
mm10_circ_0013361	circRNA	mus musculus						Alzheimer＊s disease	28669840	Characterization of circRNA-Associated-ceRNA Networks in a Senescence-Accelerated Mouse Prone 8 Brain.	Zhang S, Zhu D, Li H, Li H, Feng C, Zhang W.	Mol Ther.  2017	Up-regulated in SAMP8 brain compared to SAMP1.	RNA-seq, qRT-PCR	SAMP8 brain, SAMP1 brain												
mus_cTtn1	circRNA	mus musculus	Ttn						27531932	RBM20 Regulates Circular RNA Production From the Titin Gene.	Khan MA, Reckman YJ, Aufiero S, van den Hoogenhof MM, van der Made I, Beqqali A, Koolbergen DR, Rasmussen TB, van der Velden J, Creemers EE, Pinto YM.	Circ Res.  2016	circRNAs produced from Ig repeats and PEVK domain	RT-PCR	wildtype, heterozygous Rbm20 KO												circRNA expression is regulated by RNA-binding motif protein 20
mus_cTtn2	circRNA	mus musculus	Ttn						27531932	RBM20 Regulates Circular RNA Production From the Titin Gene.	Khan MA, Reckman YJ, Aufiero S, van den Hoogenhof MM, van der Made I, Beqqali A, Koolbergen DR, Rasmussen TB, van der Velden J, Creemers EE, Pinto YM.	Circ Res.  2016	circRNAs produced from Ig repeats and PEVK domain	RT-PCR	wildtype, heterozygous Rbm20 KO												circRNA expression is regulated by RNA-binding motif protein 20
mus_cTtn3	circRNA	mus musculus	Ttn						27531932	RBM20 Regulates Circular RNA Production From the Titin Gene.	Khan MA, Reckman YJ, Aufiero S, van den Hoogenhof MM, van der Made I, Beqqali A, Koolbergen DR, Rasmussen TB, van der Velden J, Creemers EE, Pinto YM.	Circ Res.  2016	circRNAs produced from Ig repeats and PEVK domain	RT-PCR	wildtype, heterozygous Rbm20 KO												circRNA expression is regulated by RNA-binding motif protein 20
mus_cTtn4	circRNA	mus musculus	Ttn						27531932	RBM20 Regulates Circular RNA Production From the Titin Gene.	Khan MA, Reckman YJ, Aufiero S, van den Hoogenhof MM, van der Made I, Beqqali A, Koolbergen DR, Rasmussen TB, van der Velden J, Creemers EE, Pinto YM.	Circ Res.  2016	circRNAs produced from Ig repeats and PEVK domain	RT-PCR	wildtype, heterozygous Rbm20 KO												circRNA expression is regulated by RNA-binding motif protein 20
mus_cTtn5	circRNA	mus musculus	Ttn						27531932	RBM20 Regulates Circular RNA Production From the Titin Gene.	Khan MA, Reckman YJ, Aufiero S, van den Hoogenhof MM, van der Made I, Beqqali A, Koolbergen DR, Rasmussen TB, van der Velden J, Creemers EE, Pinto YM.	Circ Res.  2016	circRNAs produced from the Z-disk and N2A region	RT-PCR	wildtype, heterozygous Rbm20 KO and Rbm20 KO mice												circRNA expression is regulated by RNA-binding motif protein 20
mus_cTtn6	circRNA	mus musculus	Ttn						27531932	RBM20 Regulates Circular RNA Production From the Titin Gene.	Khan MA, Reckman YJ, Aufiero S, van den Hoogenhof MM, van der Made I, Beqqali A, Koolbergen DR, Rasmussen TB, van der Velden J, Creemers EE, Pinto YM.	Circ Res.  2016	circRNAs produced from the Z-disk and N2A region	RT-PCR	wildtype, heterozygous Rbm20 KO and Rbm20 KO mice												circRNA expression is regulated by RNA-binding motif protein 20