RefCirc
a reference database for circRNAs validated by experiments
| hsa_circ_0037911 Details |
| Basic Information |
| circRNA | hsa_circ_0037911 |
| Alias | - |
| circBase ID | hsa_circ_0037911 |
| Host gene | GSPT1 |
| Species | homo sapiens |
| Peptide | - |
| Sequence | CACCTGTGGAATCCTCTCAAGAGGAACAGTCATTGTGTGAAGGTTCAAATTCAGCTGTTAGCATGGAACTTTCAGAACCTATTGTAGAAAATGGAGAGACAGAAATGTCTCCAGAAGAATCATGGGAGCACAAAGAAGAAATAAGTGAAGCAGAGCCAGGGGGTGGTTCCTTGGGAGATGGAAGGCCGCCAGAGGAAAGTGCCCATGAAATGATGGAGGAGGAAGAGGAAATCCCAAAACCTAAGTCTGTGGTTGCACCGCCAGGTGCTCCTAAGAAAGAGCATGTAAATGTAGTATTCATTGGGCACGTAGATGCTGGCAAGTCAACCATTGGAGGACAAATAAT |
| Expression |
| Description | The hsa_circ_0037911 expression level in EH cases were significantly higher than healthy controls (p = 0.005). There was still important significance when adjusted by logistic regression (adjusted p = 0.026). We also found that hsa_circ_0037911 was an effective marker of EH (area under curve = 0.627; p = 0.002). The levels of hsa_circ_0037911 were significantly differences in gender, BMI, smoking and drinking among EH cases. There was a positive correlation between Serum creatinine (Scr) and hsa_circ_0037911. |
| Method | qRT-PCR |
| Sample | blood samples of essential hypertension cases and controls |
| Reference |
| Pubmed ID | 29526758 |
| Trait/Disease | Hypertension |
| Title | A potential risk factor of essential hypertension in case-control study: Circular RNA hsa_circ_0037911. |
| Authors | Bao X, Zheng S, Mao S, Gu T, Liu S, Sun J, Zhang L. |
| Journal | Biochem Biophys Res Commun. 2018 |