RefCirc
a reference database for circRNAs validated by experiments

circRNA_102231 Details

Basic Information
circRNA    circRNA_102231
Alias    -
circBase ID    -
Host gene    -
Species    homo sapiens
Peptide    -
Sequence  -

Expression
Description  circRNA_102231 was upregulated in lung cancer
Method    qRT-PCR
Sample    primary LAC tissues and adjacent non-tissues, BEAS-2B and A549

Function
Description  circRNA_102231 expression was associated with TNM stage and Lymph node metastasis (P < 0.05). The area under the ROC curve (AUC) was 0.897 (Fig. 3), indicating that circRNA_102231 expression level had a potential clinical significance as a tumor marker and had the potential to help diagnosis and monitor therapeutic efficacy. circRNA_102231 inhibition suppressed lung cancer cells proliferation and invasion.
Method    loss of function
in vitro    BEAS-2B and A549
in vivo    -

Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -

Reference
Pubmed ID    29602132
Trait/Disease    Lung Cancer
Title    Increased expression of circRNA_102231 in lung cancer and its clinical significance.
Authors    Zong L, Sun Q, Zhang H, Chen Z, Deng Y, Li D, Zhang L.
Journal    Biomed Pharmacother. 2018