RefCirc
a reference database for circRNAs validated by experiments
| circMfsd6 Details |
| Basic Information |
| circRNA | circMfsd6 |
| Alias | mm9_circ_009434 |
| circBase ID | mmu_circ_0000037 |
| Host gene | Mfsd6 |
| Species | mus musculus |
| Peptide | - |
| Sequence | ATCACCATTCAGAATTTTGAAGGTCACTGACCCTAATGGTGGTGGTAAGCCATGGCTGCTGATGATAAAGTTGCTATCCTAACTGATGATGAAGAGGAGCAGAAGAGAAAATATGTGCTTGCTGATCCCTTCAATGGCATCTGCAGGGAACCAGAACCACCTTCTAATGAAACCCCCTCCTCCACAGAGACCTCAGCCATTCCCGAGGAGGAAATAGACTGGATAGAGAAACATTGTGTGAAAGTCAACAATGACCTTCTCATCTCCAAGGTGTTTTATTTTTTCTTTTACTCTGCCTATGGCTCTCTTTACCCTCTCTTACCTGTATATTATAAACAGCTGGGAATGTCACCTAGCCAGAGTGGACTGTTGGTGGGCATTCGATACTTCATTGAATTCTGCAGTGCCCCCTTCTGGGGTGTAGTTGCAGATCGTTTCAGAAAGGGCAAAATTGTCCTCCTCTTTTCGCTTCTGTGTTGGGTTTTGTTCAACCTGGGCATTGGATTTGTCAAACCTGCTACCTTGAGATGTCTACCAAAGATCCCCCCAACAGCTCACCCCACCAATGTAAGTCACCCAGTAACTGTTCTGCCAATGAACTCCTCCACTGTCGCTTTCTTTAGCACACCACCAAAATTGCTCCAGAAAAGGGACGTGCAATTGTCTGAAACAGAGCCCAATATCTCAGACATAGATCTCGTGTCAACAGCATTGACCTTGACCAGTGAACCCACACGGAGGCCCCAGACAGAGGCAATTACCCACCCTGTTACAGGCTTGATTTTGAACACAAGCACAGTGACTCTGCCCCCCACAGGAAATGTCACCAGGGAGACAACCATTGCTGTGGTCACCACCACCAAATCTTTACCATCTGATCAAGTCACCCTTGTGTATGACCAACAGGAAGTTGAGGCGATATTCTTAATTATCTTAGTGGTTGTCATAATAGGAGAATTTTTCAGTGCCTCTTCTGTCACGATTGTAGATACAGTAACCCTCCAGTACCTGGGAAAACACCGAGACCGATATGGGCTACAGCGCATGTGGGGCTCCCTGGGCTGGGGCCTGGCCATGCTGTCTGTGGGTATTGGAATCGACTATACTCATATAGATGTGCTCATTGATGGGAAGGGGTGTAAGCCCCCTGAGTACCGGAACTACCAGATTGTCTTCATCGTCTTTGGAGTTCTCATGACCATGGCCCTGATCGTTGCCACTCAGTTCCGGTTCCGCTACAACCACTTCAACAATAGTGATGGTAAAGGGAAAGAGGTGGAGATCCCACAGGTGGAAAGGGACAACTCCACAGAGTCCTCTGAAGAGACTCCAACTGCCGCGACTCACTCACAGGCCTTCAACTTCTGGGACTTGATCAAGTTGCTATGCAGTGTGCAGTATGGCTCGGTTCTGTTTGTGGCCTGGTTCATGGGTTTTGGATACGGCTTCGTGTTCACCTTTCTCTACTGGCATCTGGAAGACCTAAATGGAACTACAACCCTCTTTGGGGTCTGTTCAGTCCTGAGTCATGTGTCCGAGTTGACCGCTTACTTCTTCAGCCACAAGCTTATTGAGTTGATTGGCCATATCAG |
| Expression |
| Description | We selected several of the circRNAs, which showed a high CLR in at least one differentiation stage, and tested their expression changes with qRT-PCR and northern blots with independent biological replicates. As seen from the sequencing data, many of the analyzed circRNAs increase when linear transcript expression also increases (such as Mfsd6), but rarely by the same factor. |
| Method | qRT-PCR, northern blots |
| Sample | P19 and SH-SY5Y cells, primary forebrain neurons from CD1 mouse embryos (E17.5-E18.5) |
| Reference |
| Pubmed ID | 25921068 |
| Trait/Disease | - |
| Title | Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed. |
| Authors | Rybak-Wolf A, Stottmeister C, Glazar P, Jens M, Pino N, Giusti S, Hanan M, Behm M, Bartok O, Ashwal-Fluss R, Herzog M, Schreyer L, Papavasileiou P, Ivanov A, Ohman M, Refojo D, Kadener S, Rajewsky N. |
| Journal | Mol Cell. 2015 |