RefCirc
a reference database for circRNAs validated by experiments

mcircRasGEF1B Details

Basic Information
circRNA    mcircRasGEF1B
Alias    -
circBase ID    -
Host gene    -
Species    mus musculus
Peptide    -
Sequence  -

Expression
Description  Expression of mcircRasGEF1B was robustly induced by LPS and ODN CpG DNA, and to a lesser extent by poly I:C and Pam3CSK4.
Method    RNA-seq, qRT-PCR
Sample    RAW264.7 cells, MEF

Function
Description  mcircRasGEF1B regulates the expression of ICAM-1 in the LPS/TLR4 signaling pathway
Method    loss of function
in vitro    RAW264.7
in vivo    -

Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -

Reference
Pubmed ID    27362560
Trait/Disease    -
Title    Inducible RasGEF1B circular RNA is a positive regulator of ICAM-1 in the TLR4/LPS pathway.
Authors    Ng WL, Marinov GK, Liau ES, Lam YL, Lim YY, Ea CK.
Journal    RNA Biol. 2016