RefCirc
a reference database for circRNAs validated by experiments

circ-Strn3 Details
Basic Information
circRNA    circ-Strn3
Alias    -
circBase ID    -
Host gene    Strn3
Species    mus musculus
Peptide    -
Sequence  -
Expression
Description  Significantly changed in pLV (plasmid Lentivirus) empty, pLV Qki5, CRi empty, CRi 3+4 Qki, and CRi 5+6 Qki HL-1 cell lines. Positively regulated with Qki expression. Downregulated with doxorubicin treatment in HL-1 cells. Downregulated in mouse hearts, which had doxorubicin-induced reductions in Qki levels. Downregulated in control (pLV empty) cells exposed to doxorubicin compared with pLV Qki5-overexpressing cells.
Method    qRT-PCR
Sample    HL-1 cell lines
Function
Description  -
Method    -
in vitro    -
in vivo    -
Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -
Reference
Pubmed ID    29133306
Trait/Disease    Doxorubicin-Mediated Cardiotoxicity
Title    Quaking Inhibits Doxorubicin-Mediated Cardiotoxicity Through Regulation of Cardiac Circular RNA Expression.
Authors    Gupta SK, Garg A, Bar C, Chatterjee S, Foinquinos A, Milting H, Streckfub-Bomeke K, Fiedler J, Thum T.
Journal    Circ Res. 2018