RefCirc
a reference database for circRNAs validated by experiments
| cel_circ_0000439 Details |
| Basic Information |
| circRNA | cel_circ_0000439 |
| Alias | cel_circ_0000439,cel_circ_005708 |
| circBase ID | - |
| Host gene | crh-1 |
| Species | caenorhabditis elegans |
| Peptide | - |
| Sequence | - |
| Expression |
| Description | The presence of a back-spliced junction was confirmed by Sanger sequencing of RT-PCR products. We set out to confirm two of these high abundance circRNAs using Northern blot analysis: cel_circ_0000038 and cel_circ_0000439. Significantly upregulated in D-10 versus L4. |
| Method | qRT-PCR,sanger sequencing, northern blots |
| Sample | the C. elegans Bristol N2 wild type strain, L4 larval stage, D-1, D-7 and D-10 of adulthood. |
| Reference |
| Pubmed ID | 29298683 |
| Trait/Disease | Aging |
| Title | Global accumulation of circRNAs during aging in Caenorhabditis elegans. |
| Authors | Cortes-Lopez M, Gruner MR, Cooper DA, Gruner HN, Voda AI, van der Linden AM, Miura P. |
| Journal | BMC Genomics. 2018 |