RefCirc
a reference database for circRNAs validated by experiments

circRBFOX2.2-3 Details
Basic Information
circRNA    circRBFOX2.2-3
Alias    -
circBase ID    -
Host gene    RBFOX2
Species    gallus gallus
Peptide    -
Sequence  -
Expression
Description  up-regulated in E16 VS E11, P1 VS E11, and P1 VS E16 comparison groups.
Method    RNA-seq, qRT-PCR
Sample    six female chickens (E11, E16, and P1; each stage two individuals)
Function
Description  We validated that circRBFOX2s promoted cell proliferation through interacted with miR-206.
Method    loss of function, gain of function
in vitro    Chicken primary myoblasts, DF-1 cells, QM-7 cells
in vivo    -
Interaction
Target    gga-miR-1a-3p and gga-miR-206
Type    circRNA-miRNA
Sample    DF-1 cells
Experiment    luciferase report assay
Description    These results suggested that circRBFOX2s are able to interact with miR-1a-3p and miR-206.
ceRNA target    CCND2
Reference
Pubmed ID    29036326
Trait/Disease    Embryonic Muscle Development
Title    Circular RNAs are abundant and dynamically expressed during embryonic muscle development in chickens.
Authors    Ouyang H, Chen X, Wang Z, Yu J, Jia X, Li Z, Luo W, Abdalla BA, Jebessa E, Nie Q, Zhang X.
Journal    DNA Res. 2017