RefCirc
a reference database for circRNAs validated by experiments

Cdr1as Details
Basic Information
circRNA    Cdr1as
Alias    -
circBase ID    -
Host gene    CDR2
Species    homo sapiens
Peptide    -
Sequence  -
Expression
Description  upregulated in HCC
Method    qRT-PCR
Sample    HCC tissues and adjacent non-tumor tissues, Hep3B, HepG2, SMMC-7721, Bel7402 and HL-7702
Function
Description  Knockdown of Cdr1as suppressed the HCC cell proliferation and invasion.
Method    loss of function
in vitro    HepG2, SMMC-7721
in vivo    -
Interaction
Target    miR-7
Type    circRNA-miRNA
Sample    HCC tissues and adjacent non-tumor tissues, HepG2, SMMC-7721
Experiment    expression
Description    Cdr1asexpression was upregulated in HCC tissues and was inversely associated with the expression of miR-7. Knockdown of Cdr1as promoted theexpression of miR-7 as well as its target gene CCNE1 and PIK3CD.
ceRNA target    CCNE1 and PIK3CD
Reference
Pubmed ID    27391479
Trait/Disease    Hepatocellular Carcinoma
Title    The Circular RNA Cdr1as Act as an Oncogene in Hepatocellular Carcinoma through Targeting miR-7 Expression.
Authors    Yu L, Gong X, Sun L, Zhou Q, Lu B, Zhu L.
Journal    PLoS One. 2016