RefCirc
a reference database for circRNAs validated by experiments

hsa_circ_0000069 Details
Basic Information
circRNA    hsa_circ_0000069
Alias    hsa_circ_001061
circBase ID    hsa_circ_0000069
Host gene    STIL
Species    homo sapiens
Peptide    -
Sequence  GTCTTCCCAAAAGTTATCTTCTGGGAAGATGCCAATACATGATCACGACTCTGGTGTTGAAGATGAAGATTTTTCTCCAAGACCAATTCCTAGTCCTCATCCAGTGAGTCAGAAGATTTCTAAGATCCAACCATCAGTTCCTGAACTTTCACTTGTGTTGGATGGCAATTTCATAGAATCAAACCCTCTGCCTACTCCATTGGAAATGGTGAATAATGAAAATCCTCCTTTGATTAACCACTTGGAACACTTGAAGCCATTGCAACCCCAGCTTTATGATGAGAAACACAGTCCAGAAGTTGAAGCTGGAGAGCCTTCCTTGAGAGGAATACCAAATCAGTTAAACCAGGATAAACCAGCTCTTTTGAGACACTGCAAAGTAAGACAGCCACCTGCCTATAAGAAAGGGAACCCCCATACCAGGAACAGTATTAAACCATCTTCTCATAATGGGCCATCTCATGATATATTTGAAAAGCTCCAAACAGTTTCTGCTGGAAATGTACAAAACGAAGAGTATCCTATAAGACCCTCCACACTTAATTCTAGGCAGTCTTCTCTTGCCCCGCAGTCCCAACCACACGATTTTGTTTTTTCACCCCATAATTCAGGAAGACCAATGGAACTTCAGATACCTACTCCCCCACTGCCATCTTACTGTTCCACAAACGTTTGCAGGTGTTGTCAGCATCATAGTCATATTCAATATAGTCCGCTAAATTCTTGGCAAGGAGCAAACACAGTTGGATCCATTCAAGATGTCCAGTCTGAAGCCCTTCAAAAGCATTCATTATTTCACCCAAGTGGATGTCCAGCCCTGTACTGTAATGCATTCTGTTCTTCAAGTAGTCCTATAGCCTTGAGACCTCAGGGAGATATGGGCAGTTGTTCTCCCCACAGCAATATTGAACCATCGCCTGTGGCAAGACCGCCTTCACATATGGACTTATGTAACCCACAGCCTTGCACAGTGTGCATGCACACACCCAAGACTGAGTCAGATAATGGAATGATGGGACTATCTCCAGATGCATATCGGTTCCTCACAGAACAAGACAGACAGCTAAGACTACTTCAGGCACAG
Expression
Description  upregulated in CRC
Method    qRT-PCR
Sample    paired CRC tissues and adjacent noncancerous tissues, HCO, HT-29, LoVo, HCT-116 and SW480
Function
Description  hsa_circ_0000069 knockdown could notably inhibit cell proliferation, migration, and invasion, and induce G0/G1 phase arrest of cell cycle in vitro.
Method    loss of function
in vitro    HT-29
in vivo    -
Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -
Reference
Pubmed ID    28003761
Trait/Disease    Colorectal Cancer
Title    Comprehensive profile of differentially expressed circular RNAs reveals that hsa_circ_0000069 is upregulated and promotes cell proliferation, migration, and invasion in colorectal cancer.
Authors    Guo JN, Li J, Zhu CL, Feng WT, Shao JX, Wan L, Huang MD, He JD.
Journal    Onco Targets Ther. 2016