RefCirc
a reference database for circRNAs validated by experiments

circZKSCAN1 Details

Basic Information
circRNA    circZKSCAN1
Alias    -
circBase ID    -
Host gene    ZKSCAN1
Species    homo sapiens
Peptide    -
Sequence  -

Expression
Description  significantly lower (P<0.05) in the HCC
Method    RT-PCR and sequencing, qRT-PCR, FISH
Sample    hepatocellular carcinoma tissue specimens and paired adjacent nontumorous tissues, L02, Huh7, SMMC-7721, BEL-7402, HepG2, and Hep3B

Function
Description  Silencing circZKSCAN1 promoted cell proliferation, migration, and invasion.
Method    loss of function, gain of function
in vitro    HepG2, SMMC-7721
in vivo    6-week-old male nude mice

Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -

Reference
Pubmed ID    28211215
Trait/Disease    Hepatocellular Carcinoma
Title    ZKSCAN1 gene and its related circular RNA (circZKSCAN1) both inhibit hepatocellular carcinoma cell growth, migration, and invasion but through different signaling pathways.
Authors    Yao Z, Luo J, Hu K, Lin J, Huang H, Wang Q, Zhang P, Xiong Z, He C, Huang Z, Liu B, Yang Y.
Journal    Mol Oncol. 2017