RefCirc
a reference database for circRNAs validated by experiments

circCOL3A1-859267 Details
Basic Information
circRNA    circCOL3A1-859267
Alias    -
circBase ID    -
Host gene    COL3A1
Species    homo sapiens
Peptide    -
Sequence  -
Expression
Description  Consistent with the high throughput sequencing data, the expression of circCOL3A1-859267 in UVA group showed a 2.17 +/- 0.02 to 14.29 +/- 0.005 fold decrease as compared with the control group (P < 0.01).
Method    qRT-PCR, RNA-seq
Sample    human dermal fibroblasts
Function
Description  Overexpression of circCOL3A1-859267 inhibited UVA-induced decrease of type I collagen expression and silencing of it reduced type I collagen intensity.
Method    loss of function, gain of function
in vitro    human dermal fibroblasts
in vivo    -
Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -
Reference
Pubmed ID    28286269
Trait/Disease    Photoaging
Title    Circular RNA profiling reveals that circCOL3A1-859267 regulate type I collagen expression in photoaged human dermal fibroblasts.
Authors    Peng Y, Song X, Zheng Y, Wang X, Lai W.
Journal    Biochem Biophys Res Commun. 2017