RefCirc
a reference database for circRNAs validated by experiments
| circRNA_103827 Details |
| Basic Information |
| circRNA | circRNA_103827 |
| Alias | - |
| circBase ID | - |
| Host gene | HMGCS1 |
| Species | homo sapiens |
| Peptide | - |
| Sequence | - |
| Expression |
| Description | Up-regulated in older women. Significantly up-regulated in 20 advanced age women compared with 20 young age women. circRNA_103827 levels were significantly and positively associated with maternal age in partial correlation analysis (partial r = 0.332, P = 0.045). circRNA_103827 expressions in GCs were negatively correlated with the number of top quality embryos (r = -0.235, P = 0.036). |
| Method | qRT-PCR, microarray |
| Sample | granulosa cells |
| Reference |
| Pubmed ID | 28644873 |
| Trait/Disease | Female Infertility |
| Title | Circular RNA expression profiling of human granulosa cells during maternal aging reveals novel transcripts associated with assisted reproductive technology outcomes. |
| Authors | Cheng J, Huang J, Yuan S, Zhou S, Yan W, Shen W, Chen Y, Xia X, Luo A, Zhu D, Wang S. |
| Journal | PLoS One. 2017 |