RefCirc
a reference database for circRNAs validated by experiments

Circ-104916 Details

Basic Information
circRNA    Circ-104916
Alias    -
circBase ID    -
Host gene    -
Species    homo sapiens
Peptide    -
Sequence  -

Expression
Description  The expression of circ-104916 is downregulated in GC tissues and cell lines.
Method    qRT-PCR
Sample    paired cancer specimens and adjacent normal tissues, AGS, MKN-28, NCI-N87, MKN-45, GES-1

Function
Description  A lower expression of circ-104916 appeared in deeper invasion depth, higher tumor stage and more frequent lymphatic metastasis patients. Overexpression of circ-104916 effectively inhibited the proliferation, migration and invasion abilities of GC cells in vitro.
Method    gain of function
in vitro    BGC823, MGC803
in vivo    -

Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -

Reference
Pubmed ID    28761361
Trait/Disease    Gastric Cancer
Title    Circ-104916 is downregulated in gastric cancer and suppresses migration and invasion of gastric cancer cells.
Authors    Li J, Zhen L, Zhang Y, Zhao L, Liu H, Cai D, Chen H, Yu J, Qi X, Li G.
Journal    Onco Targets Ther. 2017