RefCirc
a reference database for circRNAs validated by experiments

hsa_circ_0045714 Details
Basic Information
circRNA    hsa_circ_0045714
Alias    -
circBase ID    hsa_circ_0045714
Host gene    UNK
Species    homo sapiens
Peptide    -
Sequence  GTGCCCATTCCTGCACAGAACCACAGGGGACACTGAGCGCAGGTACCACCTTCGTTACTACAAAACTGGAATCTGCATCCACGAGACAGACTCGAAAGGCAACTGCACCAAAAACGGCCTGCACTGCGCTTTTGCCCACGGGCCCCATGACCTCCGCTCCCCTGTCTACGACATCAGGGAGCTTCAGGCCATGGAGGCCTTGCAGAATGGCCAGACCACGGTAGAGGGGAGCATAGAGGGCCAGTCGGCTGGGGCTGCGAGCCATGCCATGATAGAAAAGATCCTCAGCGAGGAGCCTCGGTGGCAAGAGACTGCTTATGTGCTGGGGAACTATAAGACGGAGCCTTGCAAGAAGCCCCCGCGGCTGTGCCGCCAAGGCTATGCCTGTCCCTACTACCACAACAGCAAGGACCGGCGGCGGAGCCCCCGGAAGCACAAATACAGGTCGTCTCCATGTCCAAACGTCAAGCACGGGGATGAGTGGGGAGACCCTGGCAAGTGTGAGAACGGAGACGCCTGCCAGTACTGCCACACCCGCACCGAGCAGCAGTTCCACCCCGAG
Expression
Description  hsa_circ_0045714 expression was downregulated in OA tissues.
Method    qRT-PCR
Sample    OA tissues and chondrocytes
Function
Description  hsa_circ_0045714 can regulate extracellular matrix synthesis as well as proliferation and apoptosis of chondrocytes by promoting the expression of miR-193b target gene IGF1R.
Method    loss of function, gain of function
in vitro    chondrocytes
in vivo    -
Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -
Reference
Pubmed ID    28795385
Trait/Disease    Osteoarthritis
Title    Hsa_circ_0045714 regulates chondrocyte proliferation, apoptosis and extracellular matrix synthesis by promoting the expression of miR-193b target gene IGF1R.
Authors    Li BF, Zhang Y, Xiao J, Wang F, Li M, Guo XZ, Xie HB, Xia H, Chen B.
Journal    Hum Cell. 2017