RefCirc
a reference database for circRNAs validated by experiments

hsa_circ_0006528 Details
Basic Information
circRNA    hsa_circ_0006528
Alias    -
circBase ID    hsa_circ_0006528
Host gene    PRELID2
Species    homo sapiens
Peptide    -
Sequence  GTTTCCACGCTTTGAGAAGGACTGAATGAGATCATGCGCATGGCAGCTTCTCTAGGATAGCACCCTGCGTGAACACAGTAGCTGCTCAGTTAAGTCTTTGATGGGTGTGATCCTGATTCAGCTTGATCAATTCTGCAGTCATACTGGATTGTGTTTGAAAAGGTGTCCAGAAAAACCTGGCCATCTGCCTCCTGTCTTCCCAGTACCCCAACCCCATGGATAAAAATGTCATCTCAGTAAAAATCATGGAGGAAAAAAGAGATGAATCAACAGGGGTCATCTACAGAAAGAGGATTGCAATCTGTCAGAACGTGGTTCCAGAAATTTTAAGGAAGGTGAGCATTTTGAAAGTACCTAATATCCAATTAGAAGAGGAGTCATGGCTCAATCCTCGGGAAAGAAACATGGCCATACGGAGTCACTGCCTTACGTGGACACAGTATGCATCCATGAAGGAAGAGTCTGTCTTCCGGGAAAGTATGGAAAACCCAAATTG
Expression
Description  up
Method    microarray, qRT-PCR
Sample    MCF-7 and MDA-MB-231, ADM-resistant cell lines (MCF-7/ADM and MDA-MB-231/ADM), ADM resistant and ADM sensitive tissues
Function
Description  Circ 0006528 is correlated with ADM sensitivity in breast cancer
Method    -
in vitro    -
in vivo    -
Interaction
Target    miR-7-5p
Type    circRNA-miRNA
Sample    ADM-resistant human breast cancer tissues, MCF-7/ADM and MDA-MB-231/ADM cell
Experiment    expression
Description    miR-7-5p expression was increased after knocking down circ 0006528. We observed a negative correlation between circ 0006528 and miR-7-5p expression in ADM-resistant human breast cancer tissues.
ceRNA target    Raf1
Reference
Pubmed ID    28803498
Trait/Disease    Breast Cancer
Title    Screening circular RNA related to chemotherapeutic resistance in breast cancer.
Authors    Gao D, Zhang X, Liu B, Meng D, Fang K, Guo Z, Li L.
Journal    Epigenomics. 2017