RefCirc
a reference database for circRNAs validated by experiments

CircARSP91 Details

Basic Information
circRNA    CircARSP91
Alias    -
circBase ID    hsa_circ_0085154
Host gene    PABPC1
Species    homo sapiens
Peptide    -
Sequence  ACTCAGAACCGTGCTGCATACTATCCTCCTAGCCAAATTGCTCAACTAAGACCAAGTCCTCGCTGGACTGCTCAGGGTGCCAGACCTCATC

Expression
Description  downregulated by AR in an ADAR1-dependent manner
Method    microarray, qRT-PCR
Sample    MHCC-97h, LM3 and LO2 cells

Function
Description  inhibit HCC tumor growth both in vitro and in vivo
Method    loss of function, gain of function
in vitro    HepG2, MHCC-97, SK-Hep1
in vivo    male 6-8-week-old nude mice

Interaction
Target    -
Type    -
Sample    -
Experiment    -
Description    -
ceRNA target    -

Reference
Pubmed ID    29144509
Trait/Disease    Hepatocellular Carcinoma
Title    Circular RNA expression is suppressed by androgen receptor (AR)-regulated adenosine deaminase that acts on RNA (ADAR1) in human hepatocellular carcinoma.
Authors    Shi L, Yan P, Liang Y, Sun Y, Shen J, Zhou S, Lin H, Liang X, Cai X.
Journal    Cell Death Dis. 2017