RefCirc
a reference database for circRNAs validated by experiments

hsa_circ_0001564 Details
Basic Information
circRNA    hsa_circ_0001564
Alias    hsa_circ_001742
circBase ID    hsa_circ_0001564
Host gene    CANX
Species    homo sapiens
Peptide    -
Sequence  ATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCATGACAAGACCCCTTATACGATTATGTTTGGTCCAGATAAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACACAAAAACCCCAAAACGGGTATCTATGAAGAAAAACATGCTAAGAGGCCAGATGCAGATCTGAAGACCTATTTTACTGATAAGAAAACACATCTTTACACACTAA
Expression
Description  upregulated
Method    microarray, qRT-PCR
Sample    OS tissues and adjacent non-tumor tissues, NHOst, MG63, Saos-2, HOS, and U2OS
Function
Description  hsa_circ_0001564 knockdown suppressed osteosarcoma cells proliferation and promoted apoptosis.
Method    loss of function
in vitro    MG-63,HOS
in vivo    -
Interaction
Target    miR-29c-3p
Type    circRNA-miRNA
Sample    HEK293
Experiment    luciferase reporter assay
Description    A putative complementary region of hsa_circ_0001564 and miR-29c-3p was shown below and the complementary binding was confirmed by dual-luciferase reporter assay.
ceRNA target    -
Reference
Pubmed ID    29229385
Trait/Disease    Osteosarcoma
Title    Circular RNA hsa_circ_0001564 regulates osteosarcoma proliferation and apoptosis by acting miRNA sponge.
Authors    Song YZ, Li JF.
Journal    Biochem Biophys Res Commun. 2018