RefCirc
a reference database for circRNAs validated by experiments

CircRNA BCRC4 Details

Basic Information
circRNA    CircRNA BCRC4
Alias    -
circBase ID    -
Host gene    RANBP9
Species    homo sapiens
Peptide    -
Sequence  -

Expression
Description  decreased in BC
Method    qRT-PCR
Sample    UMUC3, SV-HUC-1, T24T, bladder cancer tissues and surrounding normal adjacent bladder tissues

Function
Description  Inhibitory Effects of BCRC4 Over-expression on Viability and Apoptosis of BC Cells In Vitro.
Method    gain of function
in vitro    UMUC3, T24T
in vivo    -

Interaction
Target    miR-101
Type    circRNA-miRNA
Sample    UMUC3, T24T
Experiment    expression
Description    The miR-101 level was detected after overexpression of BCRC4. The miR-101-3p expression was significantly increased in cells transfected with BCRC4 as compared with controls.
ceRNA target    EZH2

Reference
Pubmed ID    29270748
Trait/Disease    Bladder Cancer
Title    Overexpression of CircRNA BCRC4 regulates cell apoptosis and MicroRNA-101/EZH2 signaling in bladder cancer.
Authors    Li B, Xie F, Zheng FX, Jiang GS, Zeng FQ, Xiao XY.
Journal    J Huazhong Univ Sci Technolog Med Sci. 2017