RefCirc
a reference database for circRNAs validated by experiments

circ_0015756 Details
Basic Information
circRNA    circ_0015756
Alias    -
circBase ID    -
Host gene    -
Species    homo sapiens
Peptide    -
Sequence  -
Expression
Description  up
Method    microarray, qRT-PCR
Sample    hepatoblastoma and adjacent normal liver samples, QSG-7701, L02, HepG2, HuH-6, and SMMC-7221
Function
Description  circ_0015756 silencing decreases cell viability, proliferation, and invasion in vitro.
Method    loss of function
in vitro    HuH-6, SMMC-7721, HepG2
in vivo    -
Interaction
Target    miR-1250-3p
Type    circRNA-miRNA
Sample    HuH-6
Experiment    luciferase reporter assay
Description    The activity of RLuc-circ_0015756-WT was significantly reduced by miR-1250-3p mimic transfeciton, but not by other miRNA mimics transfeciton.
ceRNA target    -
Reference
Pubmed ID    29414822
Trait/Disease    Hepatoblastoma
Title    Expression Profiling Identifies Circular RNA Signature in Hepatoblastoma.
Authors    Liu BH, Zhang BB, Liu XQ, Zheng S, Dong KR, Dong R.
Journal    Cell Physiol Biochem. 2018